Results 171 to 180 of about 112,529 (303)

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra   +9 more
wiley   +1 more source

THE ESTIMATION OF GUANINE AND XANTHINE

open access: hybrid, 1941
George H. Hitchings
openalex   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich   +5 more
wiley   +1 more source

Targeting ryanodine receptors with allopurinol and xanthine derivatives for the treatment of cardiac and musculoskeletal weakness disorders. [PDF]

open access: yesProc Natl Acad Sci U S A
Miotto MC   +8 more
europepmc   +1 more source

Assessing the Quantitative Performance of Atmospheric Solids Analysis Probe‐Mass Spectrometry

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 22, 30 November 2025.
ABSTRACT Rationale Atmospheric solids analysis probe‐mass spectrometry (ASAP‐MS) is an established ambient ionisation technique that allows for the direct and rapid analysis of samples without chromatographic separation. Consequently, applications that typically benefit from ambient ionisation approaches can achieve improved sample throughput and thus ...
Alisha Henderson   +7 more
wiley   +1 more source

Microbial diversity and function in the rhizosphere microbiome: Driving forces and monitoring approaches

open access: yesAgrosystems, Geosciences &Environment, Volume 8, Issue 3, September 2025.
Abstract As an ecological unit, the rhizosphere microbiome preserves an enormous and largely unexplored diversity of microbes that play essential roles in plant health and soil functions. Omics technologies encompassing high‐throughput approaches such as metagenomics, metatranscriptomics, and metaproteomics provide helpful tools to unravel the ...
Chinenyenwa Fortune Chukwuneme   +1 more
wiley   +1 more source

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