Results 161 to 170 of about 75,914 (267)

The MHC-I related protein 1 MR1 can bind host purine catabolites. [PDF]

J Biol Chem
Abdelaal MR, Lim XY, Mak JYW, Fairlie DP, McCluskey J, Corbett AJ, Gherardin NA, Awad W, Rossjohn J.   +8 more
europepmc   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

In Silico Molecular Docking Studies and Xanthine Oxidase Inhibitory Activity of <i>Abies kawakamii</i> Leaf Extract and Its Constituent. [PDF]

Pharmaceuticals (Basel)
Huang CY, Yen PL, Hsu LS, Low JG, Huang YM, Huang SL, Ko CH, Chang HT.   +7 more
europepmc   +1 more source

Tuning the Triazolotriazine Scaffold Toward Selective A3 Adenosine Receptor Antagonists: From Molecular Recognition to Neuroprotection

ChemMedChem, Volume 21, Issue 20, 28 October 2026.
Structure‐based optimization of the triazolo‐triazine scaffold afforded highly potent and selective adenosine A3 receptor antagonists. Replacement of the classical 2‐furyl group with phenyl‐based substituents markedly improved A3 receptor affinity and selectivity.
Veronika Kost, Filippo Prencipe, Federica Panozzi, Veronica Salmaso, Sonja Kachler, Karl‐Norbert Klotz, Elisabetta Coppi, Simone Adorinni, Stefano Moro, Anna Maria Pugliese, Stephanie Federico, Giampiero Spalluto, Tatiana Da Ros   +12 more
wiley   +1 more source

Gender Differences in the Clinical and Metabolic Manifestations of Anemia in Chronic Heart Failure. [PDF]

J Clin Med
Konysbek Y, Turar A, Molotov-Luchanskiy VB, Ponamareva OA.   +3 more
europepmc   +1 more source

Ultra‐Weak Photon Emission as a By‐Product of Mitochondrial Oxidative Metabolism: Mechanisms, Limits, and Implications

Nanophotonics, Volume 15, Issue 20, 27 October 2026.
Mitochondrial oxidative metabolism generates ROS. Downstream chemiexcitation triplet carbonyls, singlet oxygen; produces ultra‐weak photon emission (UPE). Energetic bounds restrict well‐coupled respiration to extremely weak, red/NIR‐biased emission. Stronger visible UPE indicates elevated oxidative flux, linking measured photon counts to redox state ...
Samuel Crowther, Alice Attenborough, Frank Vollmer   +2 more
wiley   +1 more source

Robust excision of different purine lesions by homologs thymine DNA glycosylase and mismatch-specific uracil DNA-glycosylase. [PDF]

J Biol Chem
Espinosa KB, Ding X, Servius HW, Pidugu LS, Lee JK, Drohat AC.   +5 more
europepmc   +1 more source

Theoretical Analysis of Electronic, Vibrational Properties, and Noncovalent Interactions in Methylxanthines: Monomers to Antiparallel Dimers. [PDF]

ACS Omega
Mendoza-Báez R, Garcia-Toral D, Deriabina A, Sánchez Gutiérrez MP, Vázquez-Báez VM, Sosa Camposeco AN, Bustamante Camacho A, Hernández Cocoletzi G, Rivas-Silva JF.   +8 more
europepmc   +1 more source

Screening and Validation of Uric Acid-Lowering LAB from <i>Trachemys scripta elegans</i>. [PDF]

Microorganisms
Liu S, Shi P, Liu Y, Javed HU, Huang J, Li C, Liao Y, Wang H, Zhai B, Bu R.   +9 more
europepmc   +1 more source

One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler, Benjamin R. Duffus, Carola Schulzke   +2 more
wiley   +1 more source