Results 171 to 180 of about 58,088 (256)

Cardioprotective effects of acetate supplementation against fructose-induced cardiac injury in pregnant Wistar rats. [PDF]

Curr Res Physiol
Oyabambi AO, Agbaraolorunpo FM, Oguntebi EE, Oyakojo BC, Abena E.   +4 more
europepmc   +1 more source

Range‐Wide Genetic Population Structure and Environmental Adaptation in the Eastern Oyster (Crassostrea virginica) Provides Insight for Aquaculture

Molecular Ecology, Volume 35, Issue 15, August 2026.
ABSTRACT Selective breeding in aquaculture is necessary to establish food security and meet demand for sustainably produced protein. An informed selective breeding program requires understanding how population structure, environmental adaptation, and human activities shape natural genetic variation in wild conspecifics.
Madeline G. Eppley, Kiran Bajaj, Camille Rumberger, Elisabeth Leung, Nicole Mongillo, Jessica Small, Katie E. Lotterhos   +6 more
wiley   +1 more source

Modulation of IRAK4 as a therapeutic strategy against monosodium urate- and xanthine-induced inflammation in macrophages and HepG2 cells. [PDF]

Front Immunol
Umar S, Chang HT, Maienschein-Cline M, Ravindran S.   +3 more
europepmc   +1 more source

PbrIDD2‐PbrAPX14 Module Functions in the Ethylene‐Mediated Ripening and Senescence Process of Pear Fruit

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4878-4896, August 2026.
ABSTRACT Endogenous H2O2 participated in the ethylene‐dependent ripening and senescence process of horticultural fruit as a secondary messenger; however, the molecular mechanism beneath such a phenomenon has not been fully clarified until recently. By a conjoint analysis of metabolite, enzyme activities, gene expression profiles in AsA‐GSH cycle of ...
Libin Wang, Junpeng Niu, Xiaoyu Tan, Yuhua Xie, Li Jiang, Chen Huan, Xu Zhang, Weiqi Luo, Bing Xie, Xiaopu Ren, Guodong Wang, Yuanyuan Guo, Shaoling Zhang   +12 more
wiley   +1 more source

The roles of gut microbiota and their metabolites in uric acid-related metabolic diseases: mechanisms and therapeutic targets. [PDF]

Front Microbiol
Li H, Zhou H, Li M, Wu J, Pan L.
europepmc   +1 more source

Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY–CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4823-4843, August 2026.
ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu, Lihua Zhu, Chenyu Shao, Siyi Xie, Na Li, Xinyu Li, Fang Wang, Lvwen Peng, Huiying Jin, Fanghuizi Shang, Jianan Huang, Zhonghua Liu, Na Tian, Shuoqian Liu   +13 more
wiley   +1 more source

ROS disrupt COP9 signalosome-mediated ABCA1 protection and trigger its ubiquitination and degradation by cullin3 inhibiting cholesterol efflux and promoting foam cell formation in response to GPCR agonists. [PDF]

Redox Biol
Govatati S, Yadavalli CS, Traylor JG, Orr AW, Rao GN.   +4 more
europepmc   +1 more source

Xanthin [PDF]

, 2017
openaire   +2 more sources

Long‐Term Salt Exposure Reprograms the Nicotiana tabacum BY‐2 Suspension Proteome and Metabolome Toward Stabilization of the Core Metabolic Pathways, Protein Turnover Machinery Modifications, and Protective Metabolome Adjustments

Plant, Cell &Environment, Volume 49, Issue 8, Page 5849-5865, August 2026.
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz, Łukasz Marczak, Aleksander Strugała, Maria Tomys, Ewelina Ratajczak, Tomasz Skrzypczak, Przemysław Wojtaszek, Anna Kasprowicz‐Maluśki, Agnieszka Szuba   +8 more
wiley   +1 more source

Probiotic potential of <i>Lactiplantibacillus plantarum</i> LBK from Koumiss in reducing hyperuricemia through gut microbiota modulation. [PDF]

Front Microbiol
Zhao P, Lu Y, Xu J, Zhong H, Yan Q, Fang Z, Fan Z, Wang Q, Li Y, Li B, Wang X.   +10 more
europepmc   +1 more source