Results 11 to 20 of about 147,306 (350)

Efficient Oxidase Biosensors Based on Bioelectrocatalytic Surfaces of Electrodeposited Ferrocenyl Polycyclosiloxanes—Pt Nanoparticles

open access: yesChemosensors, 2021
The in-situ synthesis of catalytic surfaces with metallic nanoparticles must overcome the issues related to particle aggregation and polydispersity in the particle size.
Alvaro Boluda   +3 more
doaj   +1 more source

Efficient and Practical Radiosynthesis of Novel [131I]-Xanthine and [131I]-Hypoxanthine

open access: yesAtom Indonesia, 2022
Natural products (NPs) have been the basis for the discovery and development of pharmacologically relevant drug-related molecules, including radiopharmaceuticals.
H. Wongso, W. Nuraeni, E. Rosyidiah
doaj   +1 more source

A Newly Developed Method-Based Xanthine Oxidoreductase Activities in Various Human Liver Diseases

open access: yesBiomedicines, 2023
Studies evaluating xanthine oxidoreductase (XOR) activities in comprehensive liver diseases are scarce, and different etiologies have previously been combined in groups for comparison.
Ken Sato   +13 more
doaj   +1 more source

Postmortem Alteration of Purine Metabolism in Coronary Artery Disease

open access: yesMetabolites, 2023
A new approach for assisting in the diagnosis of coronary artery disease (CAD) as a cause of death is essential in cases where complete autopsy examinations are not feasible. The purine pathway has been associated with CAD patients, but the understanding
Phakchira Somtua   +6 more
doaj   +1 more source

Clinical Effects of Xanthine Oxidase Inhibitors in Hyperuricemic Patients

open access: yesMedical Principles and Practice, 2020
This review aims to critically present the available clinical evidence supporting the treatment of chronic hyperuricemia with xanthine oxidase inhibitors.
A. Cicero   +4 more
semanticscholar   +1 more source

Pathophysiology of circulating xanthine oxidoreductase: New emerging roles for a multi-tasking enzyme

open access: yesBiochimica Et Biophysica Acta - Molecular Basis of Disease, 2014
Maria Giulia Battelli   +2 more
exaly   +2 more sources

Integration of Non-Targeted Metabolomics and Targeted Quantitative Analysis to Elucidate the Synergistic Antidepressant Effect of Bupleurum Chinense DC-Paeonia Lactiflora Pall Herb Pair by Regulating Purine Metabolism

open access: yesFrontiers in Pharmacology, 2022
Graphical ...
Jiajun Chen   +13 more
doaj   +1 more source

Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site

open access: yesCommunications Biology, 2020
TRPC1/4/5 channels are non-specific cation channels implicated in a wide variety of diseases, and TRPC1/4/5 inhibitors have recently entered clinical trials.
D. J. Wright   +5 more
semanticscholar   +1 more source

Differential regulation of hypoxanthine and xanthine by obesity in a general population

open access: yesJournal of Diabetes Investigation, 2020
Uric acid is synthesized by oxidation of hypoxanthine and xanthine using a catalyzing enzyme, xanthine oxidoreductase (XOR), which can be a source of reactive oxygen species.
M. Furuhashi   +12 more
semanticscholar   +1 more source

Phân lập và khảo sát điều kiện tối ưu cho hoạt động của enzyme xanthine oxidase từ sữa bò

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2018
Mục tiêu của nghiên cứu nhằm phân lập enzyme xanthine oxidase (XO) từ sữa bò, xác định một số điều kiện tối ưu cho hoạt động của enzyme XO và chứng minh enzyme XO được phân lập có thể thay thế enzyme XO thương mại trong các nghiên cứu về ức chế hoạt tính
Từ Văn Quyền   +2 more
doaj   +1 more source

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