Results 211 to 220 of about 75,914 (267)
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Mammalian Xanthine Oxidoreductase – Mechanism of Transition From Xanthine Dehydrogenase to Xanthine Oxidase

FEBS Journal, 2008
Reactive oxygen species are generated by various biological systems, including NADPH oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute to many physiological and pathological phenomena. Mammalian xanthine dehydrogenase (XDH) can be converted to xanthine oxidase (XO), which produces both superoxide anion and ...
Emil F. Pai   +2 more
exaly   +3 more sources

Xanthine oxidase and xanthine dehydrogenase

The FASEB Journal, 1995
Xanthine oxidase and xanthine dehy‐drogenase are enzymes involved in the metabolism of purines and pyrimidines in various organisms. Their relationship to one another has been the subject of considerable debate, primarily because of their proposed roles in ischemia/reperfasion damage in tissues.
Russ Hille, Takeshi Nishino
openaire   +1 more source

Xanthine urolithiasis

Urology, 2006
Xanthine calculi are uncommonly encountered stones. When they occur, they typically do so in association with inborn metabolic disorders such as hereditary xanthinuria or Lesch-Nyhan syndrome. They may also occur in association with states of profound hyperuricemia such as myeloproliferative disease after treatment with allopurinol.
Vernon M, Pais   +4 more
openaire   +2 more sources

The reactions of chloroperoxidase in the presence of xanthine/xanthine oxidase

Biochemical and Biophysical Research Communications, 1989
Spectral data are presented which indicate that chloroperoxidase is converted to compound II during the reaction with superoxide/hydrogen peroxide generated in the xanthine/xanthine oxidase system. Upon completion of compound II formation, compound II returns back to the native state of chloroperoxidase without formation of detectable intermediates. It
D, Metodiewa, M, Pickard, H B, Dunford
openaire   +2 more sources

Aromaticity of caffeine, xanthine and the dimethyl xanthines

Tetrahedron Letters, 2014
Xanthine, caffeine and three isomeric dimethyl xanthines (theobromine, theophylline and paraxanthine) are often described as aromatic on various criteria. Here we complete the picture by assessing these molecules for aromaticity on the ring-current criterion.
Christopher M. Gibson, Patrick W. Fowler
openaire   +1 more source

Palladium compounds of xanthine and xanthine derivatives

Inorganica Chimica Acta, 1983
The biological importance of purine bases is well known. The interaction of metal ions with nucleic acids, nucleotides and nucleotides has been an active area of inorganic and structural chemistry during the last few years, and a number of recent reviews exist on the subject [1, 2].
E. Colacio   +4 more
openaire   +1 more source

[Xanthine oxidase (xanthine dehydrogenase)].

Nihon rinsho. Japanese journal of clinical medicine, 1997
Xanthine oxidase (xanthine dehydrogenase) is composed of two identical subunits of approximately 150,000 daltons. Each subunit contains four oxdation-reduction active cofactors/monomers. In vivo, the enzyme exists mostly as the dehydrogenase type (the NAD-dependent type).
S, Sumi, Y, Wada
openaire   +1 more source

Regulation of xanthine dehydrogenase and xanthine oxidase activity by hypoxia

American Journal of Physiology-Lung Cellular and Molecular Physiology, 1996
The present study determined the effect of hypoxia on xanthine dehydrogenase (XDH) and xanthine oxidase (XO) activity and gene and protein expression in cultured bovine aortic endothelial cells (BAEC). BAEC were exposed to hypoxia (3% O2) or anoxia (0% O2) for 24 or 48 h and to 24 h of hypoxia followed by 24 h of reoxygenation.
W B, Poss   +4 more
openaire   +2 more sources

Tautomerism of xanthine and alloxanthine: A model for substrate recognition by xanthine oxidase

Journal of Computer-Aided Molecular Design, 1996
Tautomerism of neutral xanthine and alloxanthine has been examined both in the gas phase and in aqueous solution. The tautomeric preference in the gas phase has been studied by means of semiempirical and ab initio quantum-mechanical computations with inclusion of correlation effects at the Møller-Plesset level, and from density-functional calculations.
Begoña Hernández   +2 more
openaire   +2 more sources

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