Results 21 to 30 of about 89,320 (324)

The synthesis, characterization and biological evaluation of a new nitric oxide donor agent [PDF]

open access: yesJournal of the Serbian Chemical Society, 2014
The synthesis of a new xanthine nitric oxide donor (TSP-81) has been discussed. The designed compound includes two structural moieties - theophylline (1,3-dimethylxanthine) and acetaminophen (4-hydroxyacetanilide) linked by the nitric oxide ...
Profire Lenuta   +6 more
doaj   +1 more source

Efficient and Practical Radiosynthesis of Novel [131I]-Xanthine and [131I]-Hypoxanthine

open access: yesAtom Indonesia, 2022
Natural products (NPs) have been the basis for the discovery and development of pharmacologically relevant drug-related molecules, including radiopharmaceuticals.
H. Wongso, W. Nuraeni, E. Rosyidiah
doaj   +1 more source

Clinical Effects of Xanthine Oxidase Inhibitors in Hyperuricemic Patients

open access: yesMedical Principles and Practice, 2020
This review aims to critically present the available clinical evidence supporting the treatment of chronic hyperuricemia with xanthine oxidase inhibitors.
A. Cicero   +4 more
semanticscholar   +1 more source

A Newly Developed Method-Based Xanthine Oxidoreductase Activities in Various Human Liver Diseases

open access: yesBiomedicines, 2023
Studies evaluating xanthine oxidoreductase (XOR) activities in comprehensive liver diseases are scarce, and different etiologies have previously been combined in groups for comparison.
Ken Sato   +13 more
doaj   +1 more source

Efficient Oxidase Biosensors Based on Bioelectrocatalytic Surfaces of Electrodeposited Ferrocenyl Polycyclosiloxanes—Pt Nanoparticles

open access: yesChemosensors, 2021
The in-situ synthesis of catalytic surfaces with metallic nanoparticles must overcome the issues related to particle aggregation and polydispersity in the particle size.
Alvaro Boluda   +3 more
doaj   +1 more source

Postmortem Alteration of Purine Metabolism in Coronary Artery Disease

open access: yesMetabolites, 2023
A new approach for assisting in the diagnosis of coronary artery disease (CAD) as a cause of death is essential in cases where complete autopsy examinations are not feasible. The purine pathway has been associated with CAD patients, but the understanding
Phakchira Somtua   +6 more
doaj   +1 more source

The Effect of Two Weeks of High-intensity Interval Training on Salvage nucleotide pathway [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2022
Purpose: The effects of exercise adaptation on improving the purine nucleotides components are inevitable, and physical activity improves the purine nucleotide salvage pathway.
Abbas Ghanbari Niaki   +1 more
doaj   +1 more source

The Synthesis and the Biological Evaluation of New Thiazolidin-4-one Derivatives Containing a Xanthine Moiety

open access: yesMolecules, 2013
Starting from theophylline (1,3-dimethylxanthine) new thiazolidin-4-one derivatives 7a1–7, 7b1–7 have been synthesized as potential antidiabetic drugs.
Lenuta Profire   +4 more
doaj   +1 more source

Simultaneous Determination of Xanthine and Hypoxanthine Using Polyglycine/rGO-Modified Glassy Carbon Electrode

open access: yesMolecules, 2023
A novel electrochemical sensor was developed for selective and sensitive determination of xanthine (XT) and hypoxanthine (HX) based on polyglycine (p-Gly) and reduced graphene oxide (rGO) modified glassy carbon electrode (GCE). A mixed dispersion of 7 μL
Ting Wang   +5 more
doaj   +1 more source

Phân lập và khảo sát điều kiện tối ưu cho hoạt động của enzyme xanthine oxidase từ sữa bò

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2018
Mục tiêu của nghiên cứu nhằm phân lập enzyme xanthine oxidase (XO) từ sữa bò, xác định một số điều kiện tối ưu cho hoạt động của enzyme XO và chứng minh enzyme XO được phân lập có thể thay thế enzyme XO thương mại trong các nghiên cứu về ức chế hoạt tính
Từ Văn Quyền   +2 more
doaj   +1 more source

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