Results 11 to 20 of about 58,088 (256)

Phân lập và khảo sát điều kiện tối ưu cho hoạt động của enzyme xanthine oxidase từ sữa bò

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2018
Mục tiêu của nghiên cứu nhằm phân lập enzyme xanthine oxidase (XO) từ sữa bò, xác định một số điều kiện tối ưu cho hoạt động của enzyme XO và chứng minh enzyme XO được phân lập có thể thay thế enzyme XO thương mại trong các nghiên cứu về ức chế hoạt tính
Từ Văn Quyền   +2 more
doaj   +1 more source

Efficient and Practical Radiosynthesis of Novel [131I]-Xanthine and [131I]-Hypoxanthine

open access: yesAtom Indonesia, 2022
Natural products (NPs) have been the basis for the discovery and development of pharmacologically relevant drug-related molecules, including radiopharmaceuticals.
H. Wongso, W. Nuraeni, E. Rosyidiah
doaj   +1 more source

Xanthine urolithiasis: Inhibitors of xanthine crystallization

open access: yesPLOS ONE, 2018
Abstract OBJECTIVE To identify in vitro inhibitors of xanthine crystallization that have potential for inhibiting the formation of xanthine crystals in urine and preventing the development of the renal calculi in patients with xanthinuria.
Grases, Felix   +3 more
openaire   +5 more sources

Xanthine dehydrogenase/xanthine oxidase and oxidative stress [PDF]

open access: yesAGE, 1997
Xanthine dehydrogenase (XDH) and xanthine oxidase (XOD) are single-gene products that exist in separate but interconvertible forms. XOD utilizes hypoxanthine or xanthine as a substrate and O2 as a cofactor to produce superoxide (·O2 (-)) and uric acid.
H Y, Chung   +7 more
openaire   +2 more sources

The Synthesis and the Biological Evaluation of New Thiazolidin-4-one Derivatives Containing a Xanthine Moiety

open access: yesMolecules, 2013
Starting from theophylline (1,3-dimethylxanthine) new thiazolidin-4-one derivatives 7a1–7, 7b1–7 have been synthesized as potential antidiabetic drugs.
Lenuta Profire   +4 more
doaj   +1 more source

The Effect of Two Weeks of High-intensity Interval Training on Salvage nucleotide pathway [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2022
Purpose: The effects of exercise adaptation on improving the purine nucleotides components are inevitable, and physical activity improves the purine nucleotide salvage pathway.
Abbas Ghanbari Niaki   +1 more
doaj   +1 more source

Fast, Efficient, and Versatile Synthesis of 6-amino-5-carboxamidouracils as Precursors for 8-Substituted Xanthines

open access: yesFrontiers in Chemistry, 2019
Substituted xanthine derivatives are important bioactive molecules. Herein we report on a new, practical synthesis of 6-amino-5-carboxamidouracils, the main building blocks for the preparation of 8-substituted xanthines, by condensation of 5,6 ...
Daniel Marx   +4 more
doaj   +1 more source

Simultaneous Determination of Xanthine and Hypoxanthine Using Polyglycine/rGO-Modified Glassy Carbon Electrode

open access: yesMolecules, 2023
A novel electrochemical sensor was developed for selective and sensitive determination of xanthine (XT) and hypoxanthine (HX) based on polyglycine (p-Gly) and reduced graphene oxide (rGO) modified glassy carbon electrode (GCE). A mixed dispersion of 7 μL
Ting Wang   +5 more
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Propentofylline Improves Thiol-Based Antioxidant Defenses and Limits Lipid Peroxidation following Gliotoxic Injury in the Rat Brainstem

open access: yesBiomedicines, 2023
Propentofylline (PROP) is a methylated xanthine compound that diminishes the activation of microglial cells and astrocytes, which are neuronal cells strongly associated with many neurodegenerative diseases.
Deborah E. M. Baliellas   +7 more
doaj   +1 more source

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