Results 11 to 20 of about 75,914 (267)
Absence of xanthine oxidase or xanthine dehydrogenase in the rabbit myocardium [PDF]
Biochemical and Biophysical Research Communications, 1986 We directly measured the activity of the enzymes xanthine oxidase and xanthine dehydrogenase in rabbit and rat hearts, using a sensitive radiochemical assay. Neither xanthine oxidase activity nor xanthine dehydrogenase activity was detected in the rabbit heart.
Grum, Cyril M. +3 more
core +8 more sources
Xanthine oxidoreductase and xanthine oxidase in human cornea. [PDF]
Histology and histopathology, 2002 Xanthine oxidoreductase (xanthine dehydrogenase + xanthine oxidase) is a complex enzyme that catalyzes the oxidation of hypoxanthine to xanthine, subsequently producing uric acid. The enzyme complex exists in separate but interconvertible forms, xanthine dehydrogenase and xanthine oxidase, which generate reactive oxygen species (ROS), a well known ...
Cejkova, J. +3 more
openaire +4 more sources
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2010 Hereditary xanthinuria type I, a defect of purine metabolism, results from a genetic deficiency of xanthine oxidase. It is an uncommon cause of stone formation in children. We report here two children with xanthine urolithiasis. The first patient was an 8-year-old boy who presented with repeated episodes of hematuria evaluated with excretory urography,
Gargah Tahar +4 more
openaire +3 more sources
Phân lập và khảo sát điều kiện tối ưu cho hoạt động của enzyme xanthine oxidase từ sữa bò
Tạp chí Khoa học Đại học Cần Thơ, 2018 Mục tiêu của nghiên cứu nhằm phân lập enzyme xanthine oxidase (XO) từ sữa bò, xác định một số điều kiện tối ưu cho hoạt động của enzyme XO và chứng minh enzyme XO được phân lập có thể thay thế enzyme XO thương mại trong các nghiên cứu về ức chế hoạt tính
Từ Văn Quyền +2 more
doaj +1 more source
Xanthine urolithiasis: Inhibitors of xanthine crystallization
PLOS ONE, 2018 Abstract OBJECTIVE To identify in vitro inhibitors of xanthine crystallization that have potential for inhibiting the formation of xanthine crystals in urine and preventing the development of the renal calculi in patients with xanthinuria.
Grases, Felix +3 more
openaire +5 more sources
Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress [PDF]
, 2009 Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating vascular oxidative stress are the NADPH oxidase and the xanthine oxidase pathways. Allopurinol, a xanthine oxidase inhibitor,
Struthers, Allan D. +2 more
core +1 more source
Effects of xanthine: xanthine oxidase on membrane function: an in vitro model of endothelial damage
, 1982 Endothelial damage caused by the oxidative species from activated granulocytes has been studied in vitro using the cell-free oxygen radical generating system, xanthine: xanthine oxidase and cultured porcine aortic endothelium.
Ager, Ann
core +4 more sources
The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]
, 2009 Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
Allan Struthers +3 more
core +1 more source
Xanthine dehydrogenase/xanthine oxidase and oxidative stress [PDF]
AGE, 1997 Xanthine dehydrogenase (XDH) and xanthine oxidase (XOD) are single-gene products that exist in separate but interconvertible forms. XOD utilizes hypoxanthine or xanthine as a substrate and O2 as a cofactor to produce superoxide (·O2 (-)) and uric acid.
H Y, Chung +7 more
openaire +2 more sources
Molecules, 2013 Starting from theophylline (1,3-dimethylxanthine) new thiazolidin-4-one derivatives 7a1–7, 7b1–7 have been synthesized as potential antidiabetic drugs.
Lenuta Profire +4 more
doaj +1 more source