Results 121 to 130 of about 34,724 (282)
Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy [PDF]
Adenine nucleotides (AdNs: ATP, ADP, AMP) are essential biological compounds that facilitate many necessary cellular processes by providing chemical energy, mediating intracellular signaling, and regulating protein metabolism and solubilization.
Brault, Jeffrey J. +2 more
core +1 more source
A biomimetic nanoplatform (CeAst@MK) is engineered for precise therapy of acute kidney injury by integrating cerium‐based antioxidation, natural flavonoid astragalin, and macrophage membrane camouflage. Featuring kidney‐targeted and pH‐responsive release, CeAst@MK scavenges ROS, suppresses inflammation, and restores renal function via modulation of ...
Shichao Zhang +9 more
wiley +1 more source
Mutation of OsSAC3, Encoding the Xanthine Dehydrogenase, Caused Early Senescence in Rice. [PDF]
Xie Z +7 more
europepmc +1 more source
The Host Coral Bleaching Response Viewed Through the Lens of Multi‐Omics
Coral bleaching is driven by multiple inputs, with heat stress and/or high irradiance being most important. The bleaching response is multifactorial with host animal species/strain and algal symbiont genotypes being critical features. Omics readout of heat stress responses includes gene expression, proteomics, metabolite, and SNP data with transcript ...
Debashish Bhattacharya +4 more
wiley +1 more source
<p><strong>Background and Objectives</strong></p><p>Prevention and treatment of hyperuricemia are based on control of uric acid levels.
F Haidari
doaj
Discoid (DLE) and systemic lupus erythematosus (SLE) are chronic inflammatory diseases of the connective tissue. Along with pathogenetic features, they have common characteristics. Immune disorders and oxidative stress are involved in pathogenesis of DLE
E. E. Mozgovaya +5 more
doaj +1 more source
Cloning and Molecular Characterization of hxA, the Gene Coding for the Xanthine Dehydrogenase (Purine Hydroxylase I) of Aspergillus nidulans [PDF]
Annie Glatigny, Claudio Scazzocchio
openalex +1 more source
Conversion of Rat Xanthine Dehydrogenase to Xanthine Oxidase during Oxidative Stress
The enzyme “xanthine oxidase” is one of the best characterized sources of superoxide anion and hydrogen peroxide. “In vivo” it mainly acts as a dehydrogenase which, by reducing NAD+, appears to be the physiologic form. Nevertheless under a variety of conditions the enzyme can undergo a conversion to an oxidase which delivers the electrons to oxygen to ...
BINDOLI, ALBERTO +4 more
openaire +2 more sources
Intestinal peroxisomes of goldfish (Carrassius auratus) - examination for hydrolase, dehydrogenase and carnitine acetyltransferase activities. [PDF]
1. Rate sedimentation and isopycnic centrifugation were used to analyse the subcellular sites of enzymes in homogenates of goldfish intestinal mucosa. 2.
Connock, Martin J. +2 more
core
Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways
Elevated SUA can lead to oxidative stress, endothelial dysfunction, inflammation and impaired function of adipocytes—all of which collectively impede insulin receptor activity and downstream signalling. Key pathways involved include activation of the NLRP3 inflammasome, suppression of AMPK and induction of mitochondrial dysfunction.
Nurshad Ali
wiley +1 more source

