Results 101 to 110 of about 169,173 (169)

A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow’s milk

Journal of Extracellular Vesicles, 2017
MicroRNAs are small gene-regulatory RNAs that are found in various biological fluids, including milk, where they are often contained inside extracellular vesicles (EVs), like exosomes.
Abderrahim Benmoussa, Sophia Ly, Si Ting Shan, Jonathan Laugier, Eric Boilard, Caroline Gilbert, Patrick Provost   +6 more
doaj   +1 more source

Comparative characteristics of blood xanthine oxidoreductase profiles in discoid and systemic lupus erythematosus

Сибирский научный медицинский журнал
Discoid (DLE) and systemic lupus erythematosus (SLE) are chronic inflammatory diseases of the connective tissue. Along with pathogenetic features, they have common characteristics. Immune disorders and oxidative stress are involved in pathogenesis of DLE
E. E. Mozgovaya, S. A. Bedina, A. S. Trofimenko, S. S. Spitsina, M. A. Mamus, I. A. Zborovskaya   +5 more
doaj   +1 more source

Xanthine oxidase and dehydrogenase activities in rat ovarian tissues

, 1992
The production of reactive oxygen species in the ovary is rapidly inducible, but the nature of the generator is unknown. One possibility is xanthine oxidase (XO), an enzyme that produces superoxide in the presence of hypoxanthine (or xanthine) and oxygen.
H. R. Behrman, Y. Margolin
core   +1 more source

Potent and Sustained Lowering of Serum Uric Acid by YJH‐012‐D, a GalNAc‐Conjugated siRNA Targeting Xanthine Dehydrogenase

Pharmacology Research & Perspectives
Hyperuricemia (HUA) is primarily driven by hepatic overproduction of urate, mediated by xanthine dehydrogenase (XDH). This preclinical study evaluates YJH‐012‐D, a N‐acetylgalactosamine (GalNAc)‐conjugated small interfering RNA (siRNA) targeting hepatic ...
Tingke Tang, Qiuying Li, Chenguang Zhang, Yongxing Wang, Lu Yang, Haibin Huang, Yujun He, Zhi Zheng, Dong Liang, Meng Wang, Yingyu Wu, Chengjiang Zhao, Wenhao Cui   +12 more
doaj   +1 more source

Gene silencing in phlebotomine sand flies : Xanthine dehydrogenase knock down by dsRNA microinjections

, 2008
Lutzomyia longipalpis are vectors of medically important visceral leishmaniasis in South America. Blood-fed adult females digest large amounts of protein, and xanthine dehydrogenase is thought to be a key enzyme involved in protein catabolism through the
Alexander, Bruce, Sant'Anna, Mauricio R, Dillon, Rod J, Bates, Paul A   +3 more
core   +3 more sources

URSOLIC ACID AND CIS-TILIROSIDE PRODUCED BY Merremia tomentosa AFFECT OVIPOSITION OF Leucoptera coffeella ON COFFEE PLANTS

Química Nova
To contribute to the development of new products to control the coffee leaf miner (Leucoptera coffeella), which is a major pest for coffee plants, this work aimed to select plant species able to produce substances active against this insect and to ...
Helvécio M. Santos Júnior, Karina C. Lopes, Dejane S. Alves, Geraldo A. Carvalho, Denilson F. Oliveira   +4 more
doaj   +1 more source

EFFECT OF GLUTATHIONE DEPLETION ON THE CONVERSION OF XANTHINE DEHYDROGENASE TO OXIDASE IN RAT-LIVER

, 1993
The ability of endogenous glutathione (GSH) to modify the activity of the enzyme xanthine oxidase (XO) in rat liver was investigated. The effect of hepatic GSH depletion on the conversion of xanthine dehydrogenase (XDH) (EC 1.1.1.204) to XO (EC 1.1.3.22)
S. DEBIASI, G. CIGHETTI, R. PARONI
core   +1 more source

Biosynthesis of Pteridines in Insects: A Review

Insects
Pteridines are important cofactors for many biological functions of all living organisms, and they were first discovered as pigments of insects, mainly in butterfly wings and the eye and body colors of insects. Most of the information on their structures
Juan Ferré
doaj   +1 more source

The role of xanthine oxidase in [PDF]

, 1995
Oxygen radicals have been proposed to be involved in the induction of liver cell damage during reperfusion after ischemia. The role of xanthine oxidase in this process and the potential of the antioxidant system have been studied in a model of in ...
Frederiks, W.M., Bosch, K.S.
core  

Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating AMPK through the purine salvage pathway

Scientific Reports
Xanthine oxidoreductase (XOR) contributes to reactive oxygen species production. We investigated the cytoprotective mechanisms of XOR inhibition against high glucose (HG)-induced glomerular endothelial injury, which involves activation of the AMP ...
Keum-Jin Yang, Hwajin Park, Yoon-Kyung Chang, Cheol Whee Park, Suk Young Kim, Yu Ah Hong   +5 more
doaj   +1 more source