Results 91 to 100 of about 169,173 (169)

Chronic kidney disease and reduced renal COX2 expression in xanthinuria: a case-control study

BMC Nephrology
Background Xanthinuria is a rare inherited metabolic disorder caused by xanthine dehydrogenase (XDH) deficiency, leading to excessive urinary xanthine excretion. It is associated with kidney stones and, in exceptional cases, renal failure.
Marie-Hélène Normand, François Gougeon, Naeem Bhojani, Mélanie Dieudé, Guillaume Bollée   +4 more
doaj   +1 more source

LACK OF CONVERSION OF XANTHINE DEHYDROGENASE TO XANTHINE-OXIDASE DURING WARM RENAL ISCHEMIA

, 1990
Irreversible transformation of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) during ischemia was determined measuring XDH and total enzyme activity in kidneys before and after 60 min of clamp of the renal pedicle.
G. CIGHETTI, M. G. KIENLE, M. DELPUPPO, R. PARONI   +3 more
core   +1 more source

Aerobic Reductive "Activation" of 5-Nitro-2-Furaldehyde Semicarbazone by Rat Liver Xanthine Dehydrogenase [PDF]

, 1983
5-Nitrofurans are synthetic antibacterial agents. In general, nitrofurans have been shown to be toxic and mutagenic to cultured mammalian cells and carcinogenic in rodents.
Kutcher, Walter
core   +1 more source

Integrated Transcriptomics and Metabolomics Analyses Provide Insights into Heat Resistance in Passion Fruit (P. edulis f. flavicarpa)

Horticulturae
Passion fruit (Passiflora edulis) is an economically important fruit worldwide. However, heat stress severely threatens its production, particularly in tropical and subtropical regions.
Lin-Hua Chen, Jiong Dong, Bing-Liang Fan, Yongcai Huang, Liu Yang, Wenguo Cai, Ling-Ling Chen   +6 more
doaj   +1 more source

Identification of xanthine dehydrogenase/xanthine oxidase as a rat Paneth cell zinc-binding protein

, 2001
Paneth cells are zinc-containing cells localized in small intestinal crypts, but their function has not been fully elucidated. Previously, we showed that an intravenous injection of diphenylthiocarbazone (dithizone), a zinc chelator, induced selective ...
Seno, Hiroshi, Fukuzawa, Hiroaki, Miyake, Naoki, Morita, Yukari, Sawada, Mitsutaka, Hiai, Hiroshi, Takaishi, Shigeo, Chiba, Tsutomu   +7 more
core   +1 more source

Modulation of IRAK4 as a therapeutic strategy against monosodium urate- and xanthine-induced inflammation in macrophages and HepG2 cells

Frontiers in Immunology
BackgroundInterleukin-1 receptor-associated kinase 4 (IRAK4) is a pivotal mediator of Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling, critically involved in innate immune activation and pro-inflammatory cytokine production ...
Sadiq Umar, Huan T. Chang, Huan T. Chang, Mark Maienschein-Cline, Sriram Ravindran   +4 more
doaj   +1 more source

A guaB Mutant Strain of Rhizobium tropici CIAT899 Pleiotropically Defective in Thermal Tolerance and Symbiosis

Molecular Plant-Microbe Interactions, 2000
Rhizobium tropici strain CIAT899 displays a high intrinsic thermal tolerance, and had been used in this work to study the molecular basis of bacterial responses to high temperature. We generated a collection of R.
Pablo M. Riccillo, Monica M. Collavino, Daniel H. Grasso, Reg England, Frans J. de Bruijn, O. Mario Aguilar   +5 more
doaj   +1 more source

Drosophila Melanogaster as a Model for Molybdo-Flavoenzyme Mediated Protection against Chemical and Physical Stress [PDF]

Aldehyde oxidase (AO) and xanthine oxidoreductase (XOR) are molybdo-flavoenzymes (MFEs) involved in the oxidation of hundreds of endogenous and exogenous aldehydes and N-heterocyclic compounds many of which are drugs, vitamins and environmental ...
Al Salhen, Khaled S
core   +1 more source

Preconditioning protects liver and lung damage in rat liver transplantation: role of xanthine/xanthine oxidase

, 2002
This study was designed to evaluate whether ischemic preconditioning could confer protection against liver and lung damage associated with liver transplantation.
Gelpí, Emili, Heredia, Nicolás, Rimola, Antonio, Fernández, Leticia, Gómez, Gloria, Marco, Alberto, Peralta, Carmen, Roselló-Catafau, Joan, Grande, Luis   +8 more
core   +1 more source

Effects of Cherry in Take Versus Allopurinol on Serum Uric Acid Levels, Biomarkers of Oxidative Stress and Hepatic Xanthine Oxidase/Xanthine Dehydrogenase Activity in Hyperuricemic Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012
<p><strong>Background and Objectives</strong></p><p>Prevention and treatment of hyperuricemia are based on control of uric acid levels.
F Haidari
doaj