Results 81 to 90 of about 169,173 (169)

X-ray crystal structure and EPR spectra of "arsenite-inhibited" Desulfovibriogigas aldehyde dehydrogenase: a member of the xanthine oxidase family [PDF]

, 2004
J. Am. Chem. Soc., 2004, 126 (28), pp 8614–8615 DOI: 10.1021/ja0490222X-ray crystallography has been used to determine the structure of arsenite-inhibited aldehyde dehydrogenase from Desulfovibrio gigas, a member of the xanthine oxidase family of ...
Romão, Maria J., Thapper, Anders, Brondino, Carlos D., Moura, José J. G., Boer, D. Roeland   +4 more
core   +1 more source

Purification and characterization of mouse liver xanthine oxidase

, 1990
: Xanthine oxidase (EC 1.1.3.22) is purified to homogeneity from mouse liver after induction with bacterial lipopolysaccharide. The enzyme has an apparent molecular weight of 300,000 in its native state and it is suggested to be constituted of two ...
Terao, M, Garattini, E, Ghezzi, P, Carpani, G, Racchi, M   +4 more
core   +2 more sources

The hitchhiker’s guide to feline xanthinuria

Journal of Feline Medicine and Surgery
Feline xanthinuria is a rare autosomal recessive disorder of purine metabolism due to genetic mutations in the xanthine dehydrogenase ( XDH ) gene. It is characterised by excessive excretion and accumulation of xanthine in the urine, which can lead to ...
Michelle M Kim, Brandon D Velie, Paul A Sheehy, Natalie F Courtman, Emily C Pritchard, Bianca Haase   +5 more
doaj   +1 more source

Relationship between plasma xanthine oxidoreductase activity and left ventricular ejection fraction and hypertrophy among cardiac patients.

PLoS ONE, 2017
Background and purposeXanthine oxidoreductase (XOR), which catalyzes purine catabolism, has two interconvertible forms, xanthine dehydrogenase and xanthine oxidase, the latter of which produces superoxide during uric acid (UA) synthesis.
Yuki Fujimura, Yohei Yamauchi, Takayo Murase, Takashi Nakamura, Shu-Ichi Fujita, Tomohiro Fujisaka, Takahide Ito, Koichi Sohmiya, Masaaki Hoshiga, Nobukazu Ishizaka   +9 more
doaj   +1 more source

Ultra‐Weak Photon Emission as a By‐Product of Mitochondrial Oxidative Metabolism: Mechanisms, Limits, and Implications

Nanophotonics, Volume 15, Issue 20, 27 October 2026.
Mitochondrial oxidative metabolism generates ROS. Downstream chemiexcitation triplet carbonyls, singlet oxygen; produces ultra‐weak photon emission (UPE). Energetic bounds restrict well‐coupled respiration to extremely weak, red/NIR‐biased emission. Stronger visible UPE indicates elevated oxidative flux, linking measured photon counts to redox state ...
Samuel Crowther, Alice Attenborough, Frank Vollmer   +2 more
wiley   +1 more source

Direct electron transfer of xanthine dehydrogenase at photo-active InGaN nanowires

Electrochemistry Communications
Indium gallium nitride (InGaN) nanowire structures were investigated as photoelectrochemical transducers for bioanalytical applications. Chopped-light voltammetry in HEPES buffer (pH 7.0) revealed a light intensity-dependent anodic photocurrent that ...
G. Göbel, G. Steingelb, H. Nell, R. Hötzel, S. Leimkühler, M. Eickhoff, F. Lisdat   +6 more
doaj   +1 more source

One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler, Benjamin R. Duffus, Carola Schulzke   +2 more
wiley   +1 more source

A tungsten supplemented diet attenuates bacterial translocation in chronic portal hypertensive and cholestatic rats: role of xanthine dehydrogenase and xanthine oxidase

, 1999
Background-Bacterial translocation (BT) plays a major role in the pathophysiological process of spontaneous infections in portal hypertension (PII) and cholestatic jaundice.
M A Pabst, G Feierl, A Kuesz, S Takahashi, Schimpl, G, Pabst, MA, Feierl, G, Takahashi, S, Kuesz, A, H Ozbey, Hollwarth, ME, G Schimpl, M E Hollwarth, Ozbey, H   +13 more
core   +1 more source

Pseudogenization of the Slc23a4 gene is necessary for the survival of Xdh-deficient mice

Scientific Reports
In most patients with type 1 xanthinuria caused by mutations in the xanthine dehydrogenase gene (XDH), no clinical complications, except for urinary stones, are observed. In contrast, all Xdh(− / −) mice die due to renal failure before reaching adulthood
Kazuki Terada, Tamaki Watanabe, Nobuhiro Yasuno, Toshio Ohtsubo, Shigeru Shibata, Kimiyoshi Ichida, Makoto Hosoyamada   +6 more
doaj   +1 more source

Recent Progress in Understanding the Mechanism of Formate Dehydrogenases

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
A hydride transfer mechanism for the molybdenum‐ and tungsten‐containing formate dehydrogenases. Recent work concerning the reaction mechanism of the molybdenum‐containing formate dehydrogenases is discussed, focusing on two alternate mechanisms of action for the enzyme involving either formation of CO2 or bicarbonate as the immediate product of the ...
Russ Hille, Dimitri Niks
wiley   +1 more source