Results 71 to 80 of about 169,173 (169)

Effects of cold water immersion versus active recovery on oxidative stress, redox gene expression and mitochondrial adaptations after strength training

Experimental Physiology, EarlyView.
Abstract We compared the acute and chronic effects of postexercise cold water immersion (CWI) and active recovery (ACT) on oxidative stress, redox‐related gene expression, mitochondrial adaptations and muscle oxidative capacity. In a crossover study, nine males completed strength sessions, followed by either 10 min CWI or ACT.
Llion A. Roberts, Chantal A. Pileggi, Nina Zeng, Vandre C. Figueiredo, James F. Markworth, Truls Raastad, David Briskey, Katsuhiko Suzuki, Jeff S. Coombes, David Cameron‐Smith, Jonathan M. Peake   +10 more
wiley   +1 more source

XANTHINE DEHYDROGENASE PROCESSES RETINOL TO RETINOIC ACID IN HUMAN MAMMARY EPITHELIAL CELLS

, 2008
Retinoic acid is considered to be the active metabolite of retinol, able to control differentiation and proliferation of epithelia. Retinoic acid biosynthesis has been widely described with the implication of multiple enzymatic activities.
TAIBI, Gennaro, NICOTRA, Concetta, DI GAUDIO, Francesca   +2 more
core   +1 more source

Measurement and Characterization of Superoxide Generation from Xanthine Dehydrogenase: A Redox-Regulated Pathway of Radical Generation in Ischemic Tissues [PDF]

, 2014
: The enzyme xanthine oxidoreductase (XOR) is an important source of oxygen free radicals and related postischemic injury. Xanthine dehydrogenase (XDH), the major form of XOR in tissues, can be converted to xanthine oxidase (XO) by oxidation of ...
Komatsu, Tomoko, Russ Hille (1311651), Masaichi-chang-il Lee, Russ Hille, Murugesan Velayutham, Velayutham, Murugesan, Tomoko Komatsu, Masaichi-Chang-il Lee (1340361), Lee, Masaichi-Chang-il, Jay L. Zweier, Jay L. Zweier (423794), Zweier, Jay L, Murugesan Velayutham (1340364), Tomoko Komatsu (29096), Hille, Russ, Zweier, Jay, Hille, Charles   +16 more
core   +1 more source

Disruption of Lactate Metabolism in the Peripheral Nervous System Leads to Motor‐Selective Deficits

Glia, Volume 74, Issue 12, December 2026.
To test the importance of lactate metabolism and shuttling between Schwann cells and neurons in the PNS, we selectively knocked out both LDHA and LDHB in motor neurons, sensory neurons, or Schwann cells. ABSTRACT Schwann cells (SCs) myelinate and provide trophic support to axons in the peripheral nervous system (PNS).
A. Joseph Bloom, Shweta Tendulkar, Amber R. Hackett, Amy Strickland, Yurie Sato‐Yamada, Liya Yuan, Wendy Dong, Joseph Ippolito, Robert E. Schmidt, Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt   +11 more
wiley   +1 more source

Metabolism of isovanillin by aldehyde oxidase, xanthine oxidase, aldehyde dehydrogenase and liver slices.

, 2005
NoAromatic aldehydes are good substrates of aldehyde dehydrogenase activity but are relatively poor substrates of aldehyde oxidase and xanthine oxidase.
Panoutsopoulos, Georgios I., Panoutsopoulos, G. I., Beedham, C., Beedham, Christine   +3 more
core   +1 more source

XDH Inhibits the Progression of Colorectal Cancer via Regulating Ferritinophagy Signaling

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
XDH inhibits the progression of CRC via mediating ferritinophagy and ferroptosis. Therefore, XDH/ferritinophagy may be a potential target for CRC. ABSTRACT Xanthine dehydrogenase (XDH) is involved in the progression of various cancer. This study aimed to investigate its potential in colorectal cancer (CRC). Gene expression was determined using RT‐qPCR,
Huiying Zhang, Meimei Yan, Mengya Li, Junjiao Gu, Xintao Wang, Jin Ding, Suxia Luo   +6 more
wiley   +1 more source

Neointimal Hyperplasia and Restenosis: Epidemiology, Pathophysiology, Animal Models, Clinical Features, Diagnosis, and Management

MedComm, Volume 7, Issue 11, November 2026.
The overall graphical diagram to summarize the pathological characteristics, pathogenesis, clinical manifestation, preclinical animal models, diagnostic methods, and intervention strategies for neointimal hyperplasia. Neointimal hyperplasia results from excessive proliferation and intimal migration of vascular smooth muscle cells (VSMCs) in the ...
Kaixu Wang, Daiyu Zhang, Yu Hu, Yixin Zhao, Xinling Wang, Long Jiang, Meixiu Jiang   +6 more
wiley   +1 more source

MODIFICATION OF THE XANTHINE-CONVERTING ENZYME OF PERFUSED RAT-HEART DURING ISCHEMIA AND OXIDATIVE STRESS

, 1988
The reversible and irreversible conversion of xanthine dehydrogenase to xanthine oxidase during ischemia/reperfusion and oxidative stress induced by hydrogen peroxide or diamide and its relationship with glutathione and protein SH groups were studied ...
RIGOBELLO, MARIA PIA, CAVALLINI, LUCIA, COASSIN M, DI LISA, FABIO, BINDOLI, ALBERTO   +4 more
core   +1 more source

XDH-1 inactivation causes xanthine stone formation in Caenorhabditis elegans which is inhibited by SULP-4-mediated anion exchange in the excretory cell.

PLoS Biology
Xanthine dehydrogenase (XDH) is a molybdenum cofactor (Moco) requiring enzyme that catabolizes hypoxanthine into xanthine and xanthine into uric acid, the final steps in purine catabolism.
Jennifer Snoozy, Sushila Bhattacharya, Brandon Johnson, Robin R Fettig, Ashley Van Asma, Chloe Brede, Sophia G Miller, Martina Ralle, Kurt Warnhoff   +8 more
doaj   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source