Association of Xanthine Oxidase and Neutrophil Activation Marker Elastase in Preeclampsia: A Case-control Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Preeclampsia is an obstetric emergency for both mother and the foetus with unknown aetiology. Delivery is the only effective way in the prompt management.
Ramya Rajshekar +4 more
doaj +1 more source
Influence of xanthine oxidase inhibitors on all-cause mortality in adults: a systematic review and meta-analysis. [PDF]
Cardiol JNowak MM +3 more
europepmc +3 more sources
Reductive activation of potential antitumor bis(aziridinyl)benzoquinones by xanthine oxidase: Competition between oxygen reduction and quinone reduction [PDF]
, 1990 The reduction of a series of 2,5-bis(1-aziridinyl)-1,4-benzoquinone (BABQ) derivatives with various 3,6 substituents by the enzyme xanthine oxidase has been studied.
Janssen, L.H.M. +5 more
core +3 more sources
Xanthine dehydrogenase/xanthine oxidase and oxidative stress [PDF]
AGE, 1997 Xanthine dehydrogenase (XDH) and xanthine oxidase (XOD) are single-gene products that exist in separate but interconvertible forms. XOD utilizes hypoxanthine or xanthine as a substrate and O2 as a cofactor to produce superoxide (·O2 (-)) and uric acid.
H Y, Chung +7 more
openaire +2 more sources
Cardiovascular and hepatic toxicity of cocaine: potential beneficial effects of modulators of oxidative stress [PDF]
, 2015 Oxidative stress (OS) is thought to play an important role in the pharmacological and toxic effects of various drugs of abuse. Herein we review the literature on the mechanisms responsible for the cardiovascular and hepatic toxicity of cocaine with ...
Antonilli, Letizia +5 more
core +9 more sources
Бюллетень сибирской медицины, 2009 In this study, we investigated the effects of preincubation with the reactive oxygen species-generating system xanthine oxidase/xanthine on Ca2+-dependent potassium permeability of erythrocyte membrane. The increase of intracellular calcium concentration
O. A. Trubacheva +6 more
doaj +1 more source
Biology, 2023 Hyperuricemia, an abnormally high level of blood uric acid, is a major risk factor for gout. Although xanthine oxidase inhibitors were clinically used to lower blood uric acid level, the concerned side effects restricted their utilization. In this study,
Kuo-Ching Huang +8 more
doaj +1 more source
Reduction of leukocyte microvascular adherence and preservation of blood-brain barrier function by superoxide-lowering therapies in a piglet model of neonatal asphyxia [PDF]
, 2019 Background: Asphyxia is the most common cause of brain damage in newborns. Substantial evidence indicates that leukocyte recruitment in the cerebral vasculature during asphyxia contributes to this damage. We tested the hypothesis that superoxide radical (
Aarti R. Shah +9 more
core +2 more sources
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Screening of methanol extracts of sixty plants from Kerman for their potential xanthine oxidase inhibitory activity [PDF]
Journal of HerbMed Pharmacology, 2017 Introduction: Gout is a chronic metabolic disease in which xanthine oxidase plays a crucial role. Many natural compounds such as various flavonoids have been reported to have inhibitory effect on xanthine oxidase.
Ahmad Gholamhoseinian +2 more
doaj