AB1038 Pharmacokinetics, pharmacodynamics and safety of nc-2500, a novel xanthine oxidoreductase inhibitor, in healthy japanese male subjects [PDF]
M. Hirano +5 more
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Letter by Tsikas Regarding Article, “Dietary Nitrate Ameliorates Pulmonary Hypertension: Cytoprotective Role for Endothelial Nitric Oxide Synthase and Xanthine Oxidoreductase” [PDF]
Dimitrios Tsikas
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Effect of NADH on hypoxanthine hydroxylation by native NAD+-dependent xanthine oxidoreductase of rat liver, and the possible biological role of this effect [PDF]
Zbigniew Kamiński, Maria Jeżewska
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Xanthine Oxidoreductase Mediates Nitrite-Induced Platelet Inhibition
Xanthine oxidoreductase (XOR) is a potential missing link in platelet hyperactivity and cardiovascular diseases. Bioconversion of NO2- to NO by XOR modulates platelet reactivity as we observed rises in plasma NO2- levels after Xdh allele deletion in mice.
Parakaw, Tipparat +2 more
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Background: Clinical findings have shown a negative correlation between the severity of depressive symptoms and serum uric acid levels in men, yet the role of metabolic regulation in the pathophysiology of depression remains largely unknown.
Songjiao Chen +6 more
doaj +1 more source
Discoid (DLE) and systemic lupus erythematosus (SLE) are chronic inflammatory diseases of the connective tissue. Along with pathogenetic features, they have common characteristics. Immune disorders and oxidative stress are involved in pathogenesis of DLE
E. E. Mozgovaya +5 more
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Xanthine oxidoreductase in essential hypertension and metabolic syndrome : Experimental studies on rodent models [PDF]
Hypertension, obesity, dyslipidemia and dysglycemia constitute metabolic syndrome, a major public health concern, which is associated with cardiovascular mortality.
Laakso, Juha
core
Investigation of aldehyde oxidase and xanthine oxidoreductase in rainbow trout (Oncorhynchus mykiss) [PDF]
Omaro A. Emhmed Aburas
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Computational Characterization of the Inhibition Mechanism of Xanthine Oxidoreductase by Topiroxostat. [PDF]
Maghsoud Y, Dong C, Cisneros GA.
europepmc +1 more source

