Results 101 to 110 of about 38,964 (184)

Comparative characteristics of blood xanthine oxidoreductase profiles in discoid and systemic lupus erythematosus

Сибирский научный медицинский журнал
Discoid (DLE) and systemic lupus erythematosus (SLE) are chronic inflammatory diseases of the connective tissue. Along with pathogenetic features, they have common characteristics. Immune disorders and oxidative stress are involved in pathogenesis of DLE
E. E. Mozgovaya, S. A. Bedina, A. S. Trofimenko, S. S. Spitsina, M. A. Mamus, I. A. Zborovskaya   +5 more
doaj   +1 more source

Asymmetric nanozymes improve cardiac purine catabolism and alleviate oxidative stress of myocardium to treat ischemic heart disease

Journal of Nanobiotechnology
Ischemic heart disease (IHD) refers to a condition with myocardial ischemia, hypoxia, and even cardiomyocyte death due to coronary artery stenosis or occlusion.
Yun Jiang, Hang Chen, Wei Chen, Liyun Zhu, Xiya Wang, Pingyuan Sun, Chanyuan Su, Renxiang Gui, Huiying Yang, Tao Yue, Kunpeng Wang, Pengyu Yang, Lizhi Dou, Linlin Zhao, Emeli Chatterjee, Guoping Li, Xuerui Chen, Jianle Chen   +17 more
doaj   +1 more source

Mechanistic studies on xanthine oxidoreductase enzymes

, 2010
In humans, the xanthine oxidoreductase enzymes are known to catalyze the final two steps of purine metabolism by converting hypoxanthine successively to xanthine and uric acid. Xanthine oxidoreductase also metabolizes a wide variety of drugs in vivo, and
Berhane, Abebe
core  

Functional food in relation to gout arthritis

Heliyon
Gouty arthritis is a crystal-induced inflammatory disease driven by hyperuricemia and monosodium urate (MSU) crystal deposition. Although pharmacological urate-lowering and anti-inflammatory therapies are effective, adverse effects, poor adherence, and ...
Yedi Herdiana
doaj   +1 more source

Computational Characterization of the Inhibition Mechanism of Xanthine Oxidoreductase by Topiroxostat. [PDF]

ACS Catal, 2023
Maghsoud Y, Dong C, Cisneros GA.
europepmc   +1 more source

Comprehensive analysis of the relationship between xanthine oxidoreductase activity and chronic kidney disease. [PDF]

iScience, 2023
Zhang Y, Ding X, Guo L, Zhong Y, Xie J, Xu Y, Li H, Zheng D.   +7 more
europepmc   +1 more source

Unveiling the anti-gout potential of terpenes isolated from Penicillium sp. supported by in silico studies

Future Journal of Pharmaceutical Sciences
Background Genus Penicillium represents one of the most prolific fungi in terms of biosynthesis of bioactive secondary metabolites. This review aims to survey the reported terpenoids isolated from different species of genus Penicillium and virtually ...
Abdelrhman M. Mohamed, Shaza H. Aly, Ahmed M. Elissawy, Mohamed A. Elanany, Rakesh K. Bachheti, Abdel Nasser B. Singab   +5 more
doaj   +1 more source

Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure. [PDF]

Respir Res, 2023
Gao L, Rafaels N, Dudenkov TM, Damarla M, Damico R, Maloney JP, Moss M, Martin GS, Sevransky J, Shanholtz C, Herr DL, Garcia JGN, Hernandez-Beeftink T, Villar J, Flores C, Beaty TH, Brower R, Hassoun PM, Barnes KC.   +18 more
europepmc   +1 more source

Human Plasma Xanthine Oxidoreductase Activity in Cardiovascular Disease: Evidence from a Population-Based Study. [PDF]

Biomedicines, 2023
Kotozaki Y, Satoh M, Nasu T, Tanno K, Tanaka F, Sasaki M.   +5 more
europepmc   +1 more source

Association of plasma xanthine oxidoreductase activity with vascular endothelial function independent of serum uric acid level: MedCity21 health examination registry. [PDF]

Int J Cardiol Heart Vasc, 2023
Kurajoh M, Fukumoto S, Akari S, Murase T, Nakamura T, Ihara Y, Imai T, Nagata Y, Morioka T, Mori K, Imanishi Y, Watanabe T, Emoto M.   +12 more
europepmc   +1 more source