Results 121 to 130 of about 77,092 (210)

Tissue- and cell-specific expression of mouse xanthine oxidoreductase gene in vivo: regulation by bacterial lipopolysaccharide

, 1995
The expression of the xanthine oxidoreductase gene was studied in various mouse organs and tissues, under basal conditions and on treatment with bacterial lipopolysaccharide.
M. Li Calzi, M. Terao, M. Kurosaki, E. Garattini, E. Scanziani   +4 more
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Protein Conformational Gating of Enzymatic Activity in Xanthine Oxidoreductase

, 2016
In mammals, xanthine oxidoreductase can exist as xanthine dehydrogenase (XDH) and xanthine oxidase (XO). The two enzymes possess common redox active cofactors, which form an electron transfer (ET) pathway terminated by a flavin cofactor.
Ken Okamoto (778187), Takeshi Nishino (2122573), Emil F. Pai (411935), Bryan T. Eger (2122570), Hiroshi Ishikita (199546)   +4 more
core   +1 more source

Crystallographic, Kinetic and Computational Studies on the Reaction Mechanism of Xanthine Oxidoreductase [PDF]

, 2011
Xanthine oxidoreductase is a molybdenum-containing enzyme which catalyzes the hydroxylation on sp2 hybridized carbon centers of a broad family of substrates including purines, aldehydes and various other heterocycles.
Cao, Hongnan
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Disrupted NAD(P) Metabolism and Xanthine Dehydrogenase in a Stress-Induced Rat Model of Depression: NMR Metabolomics Insights

Metabolites
Background: Clinical findings have shown a negative correlation between the severity of depressive symptoms and serum uric acid levels in men, yet the role of metabolic regulation in the pathophysiology of depression remains largely unknown.
Songjiao Chen, Jumeng Wei, Yongchi Wang, Yidan Yao, Haibo Wang, Jie Peng, Jinquan Li   +6 more
doaj   +1 more source

Differences in Activities of Antioxidant Superoxide Dismutase, Glutathione Peroxidase and Prooxidant Xanthine Oxidoreductase/Xanthine Oxidase in the Normal Corneal Epithelium of Various Mammals [PDF]

, 2007
Summary Under normal conditions, antioxidants at the corneal surface are balanced with the production of reactive oxygen species without any toxic effects.
J Pláteník, Č Čejka, M Vejražka, A Midelfart, S Štípek, J Kovačeva, T Ardan, J Čejková   +7 more
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Mechanistic studies on xanthine oxidoreductase enzymes

, 2011
In humans, the xanthine oxidoreductase enzymes are known to catalyze the final two steps of purine metabolism by converting hypoxanthine successively to xanthine and uric acid. Xanthine oxidoreductase also metabolizes a wide variety of drugs in vivo, and
Berhane, Abebe
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Comparative characteristics of blood xanthine oxidoreductase profiles in discoid and systemic lupus erythematosus

Сибирский научный медицинский журнал
Discoid (DLE) and systemic lupus erythematosus (SLE) are chronic inflammatory diseases of the connective tissue. Along with pathogenetic features, they have common characteristics. Immune disorders and oxidative stress are involved in pathogenesis of DLE
E. E. Mozgovaya, S. A. Bedina, A. S. Trofimenko, S. S. Spitsina, M. A. Mamus, I. A. Zborovskaya   +5 more
doaj   +1 more source

Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function [PDF]

, 2014
Coughlan, Karen, Lall, Gurprit S., Sumbayev, Vadim V., Lall, Harjinder S., Gibbs, Bernhard F., Abooali, Maryam   +5 more
core   +1 more source

Mechanistic studies on xanthine oxidoreductase enzymes

, 2010
In humans, the xanthine oxidoreductase enzymes are known to catalyze the final two steps of purine metabolism by converting hypoxanthine successively to xanthine and uric acid. Xanthine oxidoreductase also metabolizes a wide variety of drugs in vivo, and
Berhane, Abebe
core  

Drosophila Melanogaster as a Model for Molybdo-Flavoenzyme Mediated Protection against Chemical and Physical Stress

Aldehyde oxidase (AO) and xanthine oxidoreductase (XOR) are molybdo-flavoenzymes (MFEs) involved in the oxidation of hundreds of endogenous and exogenous aldehydes and N-heterocyclic compounds many of which are drugs, vitamins and environmental ...
Al Salhen, Khaled S
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