Results 141 to 150 of about 689,556 (183)

From uric acid to tophi: multistage molecular and cellular mechanisms of tophi formation. [PDF]

Front Immunol
Yan H, Yang B, Xiao N, Zhang J, Xu Y, Chen B, Zeng S, Qian H, Zhao S, Wang R, Xie J, Li Z, Xie Z.   +12 more
europepmc   +1 more source

Machine-learning and simulation identify food-derived xanthine oxidase inhibitors with in-vitro activity. [PDF]

Sci Rep
Yu B, Qin Z, Wu Y, He C.
europepmc   +1 more source

Dietary Nitrate-Rich Vegetables as Natural Modulators of Health: Mechanisms and Benefits in Ageing Populations. [PDF]

Int J Mol Sci
Kurhaluk N, Kołodziejska R, Buyun L, Kamiński P, Tkaczenko H.   +4 more
europepmc   +1 more source

Artificial metabzyme-driven metabolic reprogramming and precision oncology. [PDF]

Clin Transl Med
Hu X, Ling D.
europepmc   +1 more source

The Redox-Inflammation Axis in Atherosclerosis and Ischemic Stroke: Mechanisms, Biomarkers, and Translational Challenges. [PDF]

Int J Mol Sci
Gaczyński C, Polikowska A, Goszka M, Serwin N, Łacek U, Jerzyk A, Heryć R, Dołęgowska B, Cecerska-Heryć E.   +8 more
europepmc   +1 more source

Experimental workflows for the accurate identification of mitochondrial redox events. [PDF]

Redox Biol
Hernansanz-Agustín P, Bolaños JP, Borrás C, Cabiscol E, Campuzano V, de Cubas L, Enríquez JA, Fabregat I, Gonfaus-Ortiz G, Hidalgo E, Liesa M, Mas-Bargues C, Martínez-Ruiz A, Monsalve M, Quintana-Cabrera R, Rius-Pérez S, Sastre J, Zorzano A.   +17 more
europepmc   +1 more source

Targeting ryanodine receptors with allopurinol and xanthine derivatives for the treatment of cardiac and musculoskeletal weakness disorders. [PDF]

Proc Natl Acad Sci U S A
Miotto MC, Luna-Figueroa E, Tchagou C, Bahlouli L, Reiken S, Dridi H, Liu Y, Weninger G, Marks AR.   +8 more
europepmc   +1 more source

Xanthine Oxidoreductase Inhibitors

Handbook of Experimental Pharmacology, 2020
Xanthine oxidase inhibitors are primarily used in the clinical prevention and treatment of gout associated with hyperuricemia. The archetypal xanthine oxidase inhibitor, Allopurinol has been shown to have other beneficial effects such as a reduction in ...
Jacob George, Keeran Vickneson
exaly   +5 more sources

Some of the next articles are maybe not open access.

Related searches:

FYX-051, a Xanthine Oxidoreductase Inhibitor, Induces Nephropathy in Rats, but Not in Monkeys

Toxicologic Pathology, 2009
The present studies were performed to investigate the possible mechanism of marked species differences on nephropathy found in the long-term toxicity study of FYX-051, a xanthine oxidoreductase inhibitor. In the twenty-six-week dose toxicity study in the rat, in which FYX-051 was administered by oral gavage at 0.04, 0.2, and 1 mg/kg, xanthine-mediated ...
Naoki Ashizawa, Osamu Nagata
exaly   +5 more sources

Renoprotective Effect of the Xanthine Oxidoreductase Inhibitor Topiroxostat on Adenine-Induced Renal Injury [PDF]

American Journal of Physiology - Renal Physiology, 2016
The aim of the present study was to reveal the effect of a xanthine oxidoreductase (XOR) inhibitor, topiroxostat (Top), compared with another inhibitor, febuxostat (Feb), in an adenine-induced renal injury model. We used human liver-type fatty acid-binding protein (L-FABP) chromosomal transgenic mice, and urinary L-FABP, a biomarker of ...
Atsuko Kamijo-Ikemori, Mikako Hisamichi, Takayo Murase   +2 more
exaly   +3 more sources