Results 131 to 140 of about 6,368 (267)

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Anti-Aging Potential of Avocado Oil via Its Antioxidant Effects

Pharmaceuticals
Aging is a process characterized by tissue degeneration, increased susceptibility to chronic degenerative diseases, infections, and the appearance of neoplasms, which leads to disability and a reduction in the length and quality of life.
Olin Torres-Isidro, Marcela González-Montoya, Manuel Alejandro Vargas-Vargas, Ulises Florian-Rodriguez, Claudia Isabel García-Berumen, Rocío Montoya-Pérez, Alfredo Saavedra-Molina, Elizabeth Calderón-Cortés, Alain Raimundo Rodríguez-Orozco, Christian Cortés-Rojo   +9 more
doaj   +1 more source

Model‐Based Strategy for 6‐Mercaptopurine Treatment in Acute Lymphoblastic Leukemia Maintenance Phase: Prediction of 6‐TGN and 6‐MMP Concentrations to Optimize Treatment

Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Introduction Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The pro‐drug 6‐mercaptopurine (6‐MP), essential during maintenance, is converted into active 6‐thioguanine (6‐TGN) and toxic 6‐methylmercaptopurine (6‐MMP) metabolites, resulting in marked variability in efficacy and toxicity.
Anne Ravix, Anaïs Maillat, Eva Choong, Chantal Csajka, Monia Guidi, Francesco Ceppi   +5 more
wiley   +1 more source

Mycorrhizal Fungi Modulate the Development and Composition of Purslane (Portulaca oleracea L.) Bioactive Compounds

Agriculture
The present research focused on the physiological alterations and antioxidant potential of Portulaca oleracea L. due to mycorrhizal symbiosis with diverse strains.
Marieta Hristozkova, Katrin Valkova, Maria Geneva   +2 more
doaj   +1 more source

Treatment of stable COPD : Recent guidelines and medication update [PDF]

, 2013
Chronic Obstructive Pulmonary Disease (COPD) is a preventable cause of morbidity and mortality that poses a significant public health burden. The disease is characterized by progressively worsening airflow limitation and chronic airway inflammation with ...
Parker, William
core  

Potential Hypoglycemic, Hypolipidemic, and Hypouricemic Bioactive Components From Ampelopsis grossedentata Explored by Affinity Ultrafiltration With Three Enzyme Targets

eFood, Volume 7, Issue 2, April 2026.
By integrating bioaffinity ultrafiltration coupled with HPLC‐MS/MS, this study identified quercetin, myricetrin, dihydromyricetin, and taxifolin from Ampelopsis grossedentata as key inhibitors of α‐glucosidase, pancreatic lipase, and xanthine oxidase, highlighting the promising potential of A.
Siyang Mao, Chu Chu, Yanzhi Xiong, Mengjia Xu, Jian Yang, Mingquan Guo   +5 more
wiley   +1 more source

Potential to Improve Nitrogen Fertilizer Use Efficiency and Mitigate Pollution in Tropical Pastures Grazed by Sheep

New Zealand Journal of Agricultural Research, Volume 69, Issue 2, April 2026.
We hypothesize that increasing N application rates will affect N use efficiency (NUE) for lambs grazing warm‐season annual grasses. We evaluated the effect of N fertilizer application rates (50, 100, 200, and 400 kg N/ha) on forage pearl millet (Pennisetum glaucum (L.) R.) and animal responses: N balance and NUE per animal and per area basis.
Diego Bitencourt de David, Cesar Henrique Espírito Candal Poli, Eduardo Bohrer de Azevedo, Jean Víctor Savian, Marta Moura Kohmann, Paulo César de Faccio Carvalho   +5 more
wiley   +1 more source

Comparison of the effects of desmopressin and pethedin in treatment of acute renal colic [PDF]

, 2006
Background and aim: Renal colic pain is a problem in emergency rooms and for some out- patients. Narcotic drugs are the drugs of choice for pain relief in these patients, but possible abuse, inaccessibility and some complications limit their usage ...
mohammad alibeyg, F., Rafieyan, M.
core  

Differential Analysis of IAA Anabolism Pathway Based on Bacillus cereus, Bacillus subtilis and Bacillus safensis Genome

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Three Bacillus species isolated from Platycladus orientalis rhizosphere in Taihang Mountains: Bacillus cereus has 3 IAA synthesis pathways (TAM, IAM, IPyA); Bacillus subtilis has IAM/IPyA; and Bacillus safensis only has IPyA (via whole‐genome sequencing).
Dongyue Hou, Xuejie Zhai, Kezhong Zhang, Jinteng Cui   +3 more
wiley   +1 more source

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

Equine Veterinary Education, Volume 38, Issue 4, Page 206-219, April 2026.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source