Results 161 to 170 of about 42,906 (302)

Development of subtype-selective covalent ligands for the adenosine A2B receptor by tuning the reactive group. [PDF]

open access: yesRSC Med Chem, 2022
Beerkens BLH   +9 more
europepmc   +1 more source

Pharmacokinetics, pharmacodynamics, and safety interaction study of tunodafil hydrochloride and alcohol: A randomized, blinded, placebo‐controlled, three‐cycle crossover study in Chinese healthy men

open access: yesAndrology, Volume 14, Issue 2, Page 466-479, February 2026.
Abstract Objectives This study aimed to evaluate the pharmacodynamic effects of administering tunodafil hydrochloride with alcohol on blood pressure and heart rate in healthy Chinese males, and to investigate the mutual pharmacokinetic interactions and safety of the combination.
Dingyuan Hu   +18 more
wiley   +1 more source

Enantioconvergent Access to Chiral S(VI) Stereocenters by Kinetic Resolution of Sulfonimidoyl Chlorides

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
An enantioconvergent approach for the kinetic resolution of S(VI) stereocenters that leverages the electrophilic reactivity of the chiral sulfur atom is described. The catalytic process provides access to sulfonimidoyl chlorides and sulfonimidates, which are among the least studied S(VI) functionalities.
Arko Das   +10 more
wiley   +2 more sources

Potential of doxofylline in the treatment of chronic obstructive airway diseases (Review). [PDF]

open access: yesBiomed Rep
Covantsev S   +6 more
europepmc   +1 more source

Mesoionic xanthine analogs: antagonists of adenosine receptors

open access: green, 1984
Richard A. Glennon   +3 more
openalex   +1 more source

Pharmacogenomics of Thiopurine Drugs: A Bench‐To‐Bedside Success Story in Thailand

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Thiopurine drugs are the cornerstone treatment for many diseases such as acute lymphoblastic leukemia (ALL), organ rejection, inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other autoimmune diseases.
Mohitosh Biswas   +3 more
wiley   +1 more source

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