Results 201 to 210 of about 4,011 (296)

Erratum to: One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines

Chemistry Central Journal, 2017
Samar A. El-Kalyoubi, Eman A. Fayed, Ahmed S. Abdel-Razek   +2 more
doaj   +1 more source

Fecal metabolome alterations in infants at risk of developing allergies during the first year of life. [PDF]

Metabolomics
Savova MV, Zhu P, Kindt A, TEMPO study team, Wopereis H, Belzer C, Harms AC, Hankemeier T.   +7 more
europepmc   +1 more source

Zingerone Alleviates Acetaminophen‐Induced Liver Damage by Regulating Oxidative Stress, Inflammation, Apoptosis, Endoplasmic Reticulum Stress, and Autophagy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Mechanism of action of zingerone on acetaminophen‐induced liver damage. ABSTRACT The aim of this study is to investigate the protective effect of zingerone (ZNG), an antioxidant agent, against acetaminophen (APAP)‐induced liver damage, which is used as an analgesic and antipyretic. For this purpose, twenty‐eight male rats were divided into four groups:
Serpil Aygörmez, Mustafa Makav, Sevda Eliş Yıldız, Elif Dalkılınç, Mushap Kuru, Şaban Maraşlı   +5 more
wiley   +1 more source

Comparative Evaluation and Profiling of Chemical Tools for the Nuclear Hormone Receptor Family 2. [PDF]

ACS Pharmacol Transl Sci
Lewandowski M, Busch R, Marschner JA, Merk D.   +3 more
europepmc   +1 more source

Isobavachin Attenuates Renal and Cardiac Injury in Chronic Hyperuricemia via Modulation of NF‐κB and NLRP3 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Isobavachin alleviates HUA‐induced oxidative stress, inflammation, and fibrosis in the kidney and heart, potentially through its dual role in promoting UA excretion and inhibiting NF‐κB signaling and NLRP3 inflammasome activation. ABSTRACT Hyperuricaemia (HUA) is a recognized risk factor for cardiovascular and renal diseases.
Yongmei Li, Yuexin Xu, Wenjie Ye, Zeqi Yu, Zhenkun Wu, Xinyi Liu, Xuhong Huang, Jianxin Pang, Zean Zhao, Ting Wu   +9 more
wiley   +1 more source

Distinguishing Isomeric Caffeine Metabolites through Protomers and Tautomers Using Cryogenic Gas-Phase Infrared Spectroscopy. [PDF]

Anal Chem
Geue N, Prabhu GRD, Renzi E, Walton-Doyle C, Meijer G, von Helden G, Pagel K.   +6 more
europepmc   +1 more source

Barbaloin Attenuates Cisplatin‐Induced Hippocampal Neurotoxicity by Suppressing Oxidative Stress, Neuroinflammation, and Apoptosis: In Vivo and In Silico Evidence

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Important Aloe vera phytonutrient, barbaloin, inhibits the neurotoxic effects of cisplatin on hippocampus, which involves reducing oxidative stress, neuroinflammation, and apoptosis, thereby restoring the balance of neurotransmitters and cognition. The generated docking structures with 100‐ns molecular dynamics simulations show stable energy‐minimized ...
Rahamat Unissa Syed, Rihab Akasha, Nancy Mohammad Elafandy, Sally Hassan Abobaker, Afrah Nashmi Al‐Shammari, Lama Abdullah Altwalah, Rawabi Mohammed Menwer Aldafeeri, Amira Ibrahim Mohammed Ahmed Alfaki, Mohd Sajjad Ahmad Khan, Ashgan A. Ahmed   +9 more
wiley   +1 more source

Benchmarking untargeted metabolomics data quality with allopurinol-induced perturbations. [PDF]

Metabolomics
Vasskog T, Heinsvig PJ, Sharashova E, Hansen T, Myhre TN, Mardal M.   +5 more
europepmc   +1 more source

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi, Alastair G. McEwan, Ulrike Kappler   +2 more
wiley   +1 more source

Exploratory untargeted metabolomics analysis reveals differences in metabolite profiles in pregnant people exposed vs. unexposed to E-cigarettes secondhand in the NYU children's health and environment study. [PDF]

Metabolomics
Cavalier H, Long SE, Rodrick T, Siu Y, Jacobson MH, Afanasyeva Y, Sherman S, Liu M, Kahn LG, Jones DR, Trasande L.   +10 more
europepmc   +1 more source