Results 231 to 240 of about 42,906 (302)

1-Methylxanthine enhances memory and neurotransmitter levels. [PDF]

PLoS One
Jäger R, Abou Sawan S, Orrú M, Tinlsey GM, Purpura M, Wells SD, Liao K, Godavarthi A.   +7 more
europepmc   +1 more source

Ideal efficacy photoswitches for TRPC4/5 channels harness high potency for spatiotemporally-resolved control of TRPC function in live tissues

Müller M, Niemeyer K, Ojha NK, Porav SA, Vinayagam D, Urban N, Büchau F, Oleinikov K, Makke M, Bauer CC, Johnson AV, Muench SP, Zufall F, Bruns D, Schwarz Y, Raunser S, Leinders-Zufall T, Bon RS, Schaefer M, Thorn-Seshold O.   +19 more
europepmc   +1 more source

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Xanthine urolithiasis

Urology, 2006
Xanthine calculi are uncommonly encountered stones. When they occur, they typically do so in association with inborn metabolic disorders such as hereditary xanthinuria or Lesch-Nyhan syndrome. They may also occur in association with states of profound hyperuricemia such as myeloproliferative disease after treatment with allopurinol.
Vernon M, Pais, Gregory, Lowe, Costas D, Lallas, Glenn M, Preminger, Dean G, Assimos   +4 more
openaire   +2 more sources

Xanthine oxidase and xanthine dehydrogenase

The FASEB Journal, 1995
Xanthine oxidase and xanthine dehy‐drogenase are enzymes involved in the metabolism of purines and pyrimidines in various organisms. Their relationship to one another has been the subject of considerable debate, primarily because of their proposed roles in ischemia/reperfasion damage in tissues.
Russ Hille, Takeshi Nishino
openaire   +1 more source

Mammalian xanthine oxidoreductase – mechanism of transition from xanthine dehydrogenase to xanthine oxidase

The FEBS Journal, 2008
Reactive oxygen species are generated by various biological systems, including NADPH oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute to many physiological and pathological phenomena. Mammalian xanthine dehydrogenase (XDH) can be converted to xanthine oxidase (XO), which produces both superoxide anion and ...
Tomoko, Nishino, Ken, Okamoto, Bryan T, Eger, Emil F, Pai, Takeshi, Nishino   +4 more
openaire   +2 more sources

[Xanthine oxidase (xanthine dehydrogenase)].

Nihon rinsho. Japanese journal of clinical medicine, 1997
Xanthine oxidase (xanthine dehydrogenase) is composed of two identical subunits of approximately 150,000 daltons. Each subunit contains four oxdation-reduction active cofactors/monomers. In vivo, the enzyme exists mostly as the dehydrogenase type (the NAD-dependent type).
S, Sumi, Y, Wada
openaire   +1 more source

Xanthine Oxidoreductase Inhibitors

2020
Xanthine oxidase inhibitors are primarily used in the clinical prevention and treatment of gout associated with hyperuricemia. The archetypal xanthine oxidase inhibitor, Allopurinol has been shown to have other beneficial effects such as a reduction in vascular reactive oxygen species and mechano-energetic uncoupling.
Vickneson, Keeran, George, Jacob
openaire   +3 more sources

Palladium compounds of xanthine and xanthine derivatives

Inorganica Chimica Acta, 1983
The biological importance of purine bases is well known. The interaction of metal ions with nucleic acids, nucleotides and nucleotides has been an active area of inorganic and structural chemistry during the last few years, and a number of recent reviews exist on the subject [1, 2].
E. Colacio, J.M. Salas, M.A. Romero, A. Sánchez, M. Nogueras   +4 more
openaire   +1 more source