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[Xanthine oxidase (xanthine dehydrogenase)].
Nihon rinsho. Japanese journal of clinical medicine, 1997Xanthine oxidase (xanthine dehydrogenase) is composed of two identical subunits of approximately 150,000 daltons. Each subunit contains four oxdation-reduction active cofactors/monomers. In vivo, the enzyme exists mostly as the dehydrogenase type (the NAD-dependent type).
S, Sumi, Y, Wada
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Xanthine Oxidoreductase Inhibitors
2020Xanthine oxidase inhibitors are primarily used in the clinical prevention and treatment of gout associated with hyperuricemia. The archetypal xanthine oxidase inhibitor, Allopurinol has been shown to have other beneficial effects such as a reduction in vascular reactive oxygen species and mechano-energetic uncoupling.
Vickneson, Keeran, George, Jacob
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Palladium compounds of xanthine and xanthine derivatives
Inorganica Chimica Acta, 1983The biological importance of purine bases is well known. The interaction of metal ions with nucleic acids, nucleotides and nucleotides has been an active area of inorganic and structural chemistry during the last few years, and a number of recent reviews exist on the subject [1, 2].
E. Colacio +4 more
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Fullerene Derivatives Attenuate Bronchoconstriction Induced by Xanthine-Xanthine OxidaseX
Fullerene Science and Technology, 1997Abstract The intratracheal instillation of xanthine-xanthine oxidase caused a marked decrease in dynamic respiratory compliance, indicating airway constriction. The constriction was significantly attenuated by fullerenol-1, but not by other agents or receptor antagonists.
Yih-Loong Lai +2 more
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Journal of the American Pharmaceutical Association (Scientific ed.), 1952
An investigation was undertaken of the effect on the purine metabolism of the rat of 2-amino-4-hydroxy-6-formyl pteridine, known to inhibit xanthine oxidase, and sodium bromide, reported to retard uricopoiesis. Neither the intraperitoneal administration of the pteridine nor the oral administration of sodium bromide significantly lowered the tissue ...
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An investigation was undertaken of the effect on the purine metabolism of the rat of 2-amino-4-hydroxy-6-formyl pteridine, known to inhibit xanthine oxidase, and sodium bromide, reported to retard uricopoiesis. Neither the intraperitoneal administration of the pteridine nor the oral administration of sodium bromide significantly lowered the tissue ...
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Ischaemic Brain Oedema and Xanthine-Xanthine Oxidase System
1990The formation of oxygen-derived free radicals in cerebral ischaemia has been implicated in altering the BBB permeability, cause oedema and tissue damage. However little attention has been paid regarding the involvement of xanthine oxidase in the cerebral ischaemic events.
Y, Kinuta, H, Kikuchi, M, Ishikawa
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1980
The observation of a weak reddish fluorescence to ultraviolet light at 253 nm wave length in a chromatographic plate destined to identify purine bases contained in a vesical calculus of V.Y. (11-7), member of our second family of hereditary xanthinuria,1, made us suspect the presence of porphyrins or of pharmacological agents adsorbed by the purines ...
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The observation of a weak reddish fluorescence to ultraviolet light at 253 nm wave length in a chromatographic plate destined to identify purine bases contained in a vesical calculus of V.Y. (11-7), member of our second family of hereditary xanthinuria,1, made us suspect the presence of porphyrins or of pharmacological agents adsorbed by the purines ...
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