Results 11 to 20 of about 5,171 (202)

The Bioavailability of Xanthohumol in Humans and the Influence of Formulation and Dose: Randomized Controlled Trial Data. [PDF]

Mol Nutr Food Res
The effects of two different doses of micellar and native xanthohumol on plasma kinetics were investigated in 12 healthy men and women. Micellization significantly improved the bioavailability of xanthohumol. A subsequent placebo‐controlled study on the acute effects of xanthohumol on resting energy expenditure, blood pressure, and heart rate in 16 ...
Brehmer-Henkel S, Diekmann C, Eickeler M, Maris R, Kopp C, Coenen M, Németh R, Stoffel-Wagner B, Sus N, Frank J, Egert S.   +10 more
europepmc   +2 more sources

Microbial Conjugation Studies of Licochalcones and Xanthohumol [PDF]

International Journal of Molecular Sciences, 2021
Microbial conjugation studies of licochalcones (1–4) and xanthohumol (5) were performed by using the fungi Mucor hiemalis and Absidia coerulea. As a result, one new glucosylated metabolite was produced by M. hiemalis whereas four new and three known sulfated metabolites were obtained by transformation with A. coerulea.
Han, Fubo, Xiao, Yina, Lee, Ik-Soo
openaire   +2 more sources

Selective Antimicrobial and Cytotoxic Effects of Hop Compounds to Combat Poultry Antimicrobial Resistance. [PDF]

Microbiologyopen
Phytogenic feed additives (PFAs) like hop (Humulus lupulus) offer a sustainable alternative to antibiotics in the expanding global poultry market. This study tested five hop‐derived compounds for antibacterial activity against Micrococcus luteus and Bacillus subtilis, and for their cytotoxicity in chicken cells.
Kober L, Castiglione K.
europepmc   +2 more sources

A Combination of Xanthohumol and Ursolic Acid in the Diet Leads to Synergistic Inhibition of Prostate Cancer Progression. [PDF]

Mol Carcinog
ABSTRACT Prostate cancer (PCa) is the second most common cancer and second leading cause of cancer death for American men. Chemoprevention by using phytochemicals offers a promising approach to improve outcomes due to their ability to act on cancer cell metabolism and growth while maintaining low toxicity profiles.
Clark R, Saha A, Lavender Hackman G, Friedman CA, Gorgoglione R, Tiziani S, DiGiovanni J.   +6 more
europepmc   +2 more sources

Synthesis of xanthohumol and xanthohumol-d₃ from naringenin

RSC Advances, 2021
A six-step synthesis of xanthohumol and its d3-derivative from easily accessible naringenin is reported.
Joanna Andrusiak, Kinga Mylkie, Małgorzata Wysocka, Jacek Ścianowski, Andrzej Wolan, Marcin Budny   +5 more
openaire   +3 more sources

Inverse Molecular Docking Elucidating the Anticarcinogenic Potential of the Hop Natural Product Xanthohumol and Its Metabolites

Foods, 2022
Natural products from plants exert a promising potential to act as antioxidants, antimicrobials, anti-inflammatory, and anticarcinogenic agents. Xanthohumol, a natural compound from hops, is indeed known for its anticarcinogenic properties.
Katarina Kores, Zala Kolenc, Veronika Furlan, Urban Bren   +3 more
doaj   +1 more source

Safety and Tolerability of Xanthohumol in Adults With Crohn's Disease: Results of a Triple‐Masked, Randomized, Placebo‐Controlled Phase 2 Trial [PDF]

Mol Nutr Food Res
Adults with active Crohn's disease (n = 20) received 24 mg/day of xanthohumol (XN), a bioactive compound derived from Humulus lupulus (hops), for 8 weeks. The study evaluated safety and tolerability through clinical laboratory measures, adverse events, vital signs, anthropometrics, health−related quality of life, and adherence.
Bradley R, A. Staab C, E. Jamieson P, O. Langley B, O. Metz T, F. Stevens J.   +5 more
europepmc   +2 more sources

Bioactive Compounds Obtained from Polish “Marynka” Hop Variety Using Efficient Two-Step Supercritical Fluid Extraction and Comparison of Their Antibacterial, Cytotoxic, and Anti-Proliferative Activities In Vitro

Molecules, 2021
Given the health-beneficial properties of compounds from hop, there is still a growing trend towards developing successful extraction methods with the highest yield and also receiving the products with high added value.
Katarzyna Klimek, Katarzyna Tyśkiewicz, Malgorzata Miazga-Karska, Agnieszka Dębczak, Edward Rój, Grazyna Ginalska   +5 more
doaj   +1 more source

Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and in vivo

Frontiers in Cell and Developmental Biology, 2020
Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer-related death worldwide. Xanthohumol is a prenylated flavonoid isolated from hops.
Shuying Yin, Shuying Yin, Mengqiu Song, Mengqiu Song, Ran Zhao, Ran Zhao, Xuejiao Liu, Xuejiao Liu, Woo Kyu Kang, Jeong Min Lee, Young Eun Kim, Chengjuan Zhang, Jung-Hyun Shim, Kangdong Liu, Kangdong Liu, Kangdong Liu, Zigang Dong, Zigang Dong, Zigang Dong, Mee-Hyun Lee, Mee-Hyun Lee, Mee-Hyun Lee   +21 more
doaj   +1 more source

Xanthohumol-Enriched Beer Does Not Exert Antitumorigenic Effects on HeLa Cell Line In Vivo

Molecules, 2023
Xanthohumol is a hop-derived flavonoid that has been widely examined for its health-protecting and antitumorigenic properties, but not yet in a natural beer matrix.
Anna Júlia Éliás, Lajos Balogh, Tomáš Brányik, Erzsébet Mák, Éva Csajbókné Csobod, Márta Veresné Bálint, Csilla Benedek   +6 more
doaj   +1 more source