Results 71 to 80 of about 19,512 (146)

Nuclear receptors in metabolism and diseases: Mechanistic and therapeutic insights

Pharmacological Research
Nuclear receptors (NRs) are ligand-activated transcription factors that function as metabolic sensors, integrating endogenous and xenobiotic signals to regulate gene networks controlling metabolism, immunity, and cellular homeostasis.
Chen-Ying Zhu, Pei-Han Yu, Qi Sun, De-Fei Hong, Chang Yang, Hua Naranmandura   +5 more
doaj   +1 more source

Correction to "Microbial Metabolites as Ligands to Xenobiotic Receptors: Chemical Mimicry as Potential Drugs of the Future". [PDF]

Drug Metab Dispos, 2023
europepmc   +1 more source

Orphan Nuclear Receptors: The Exotics of Xenobiotics [PDF]

Journal of Biological Chemistry, 2001
W, Xie, R M, Evans
openaire   +2 more sources

The Nuclear Xenobiotic Receptor CAR [PDF]

Molecular Cell, 2004
Suino, Kelly, Peng, Li, Reynolds, Ross, Li, Yong, Cha, Ji-Young, Repa, Joyce J., Kliewer, Steven A., Xu, H.Eric   +7 more
openaire   +1 more source

Targeting xenobiotic receptors PXR and CAR in human diseases. [PDF]

Drug Discov Today, 2015
Banerjee M, Robbins D, Chen T.
europepmc   +1 more source

An estrogen receptor β-selective agonist inhibits non-alcoholic steatohepatitis in preclinical models by regulating bile acid and xenobiotic receptors. [PDF]

Exp Biol Med (Maywood), 2017
Ponnusamy S, Tran QT, Thiyagarajan T, Miller DD, Bridges D, Narayanan R.   +5 more
europepmc   +1 more source

Pregnane xenobiotic receptors and membrane progestin receptors: role in neurosteroid-mediated motivated behaviours. [PDF]

J Neuroendocrinol, 2013
Frye CA, Koonce CJ, Walf AA.
europepmc   +1 more source

[Nuclear receptors and metabolism of xenobiotics].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2009
S. N. Larina, I. V. Ignatiev, N. V. Chebyshev, V. G. Kukes   +3 more
openaire   +2 more sources

Understanding the Chemosensory and Detoxification Mechanisms in the Oriental Fruit Fly, <i>Bactrocera dorsalis</i>. [PDF]

Insects
Jaffar S, Lu Y.
europepmc   +1 more source

Integrated Bulk and Single-Cell Transcriptomic Analysis Reveals Xenobiotic Metabolism Genes Drive Progression From Liver Cirrhosis to Hepatocellular Carcinoma. [PDF]

Hum Mutat
Xu H, Li Y, Zhao R, Ma S, Hu N, Yu S, Lv X.   +6 more
europepmc   +1 more source