Results 101 to 110 of about 167,815 (303)

interleukin-11 induces and maintains progenitors of different cell lineages during Xenopus tadpole tail regeneration

open access: yesNature Communications, 2017
Xenopus laevis tadpoles have maintained their ability to regenerate various organs. Here, the authors show that interleukin-11 is necessary for organ regeneration, by inducing and maintaining undifferentiated progenitors across cell lineages during ...
Hiroshi Tsujioka   +5 more
doaj   +1 more source

Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho   +2 more
wiley   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler   +7 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Toxicity of Four Common Environmental Chemicals Across Caenorhabditis elegans Life Stages Supporting the One Health Concept

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Pesticides and pharmaceuticals are among the most common chemical groups in waterbodies and soils, and their universal distribution raises concerns about potential adverse effects on nontarget organisms and humans. Reproductive output disruption is of particular concern, as it transposes effects from the individual to the next generations at ...
Fábio Campos   +3 more
wiley   +1 more source

Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack. [PDF]

open access: yesNew Phytol
Summary NRT1/PTR FAMILY (NPF) transporters play crucial roles in plant physiology and development due to their involvement in nitrogen nutrition and their ability to transport multiple signaling molecules and metabolites. Whereas most eukaryotic and prokaryotic NPF orthologs are peptide transporters, most flowering plant NPF transport other substrates ...
Morales de Los Ríos L   +6 more
europepmc   +2 more sources

Ecophysiology of an Avian Invader: Body Condition and Metabolic Rate Adjustments to Ambient Temperature

open access: yesIntegrative Zoology, EarlyView.
This study examines the ecophysiological responses of common waxbills to temperature variation in Portugal. We measured body condition and basal metabolic rate (BMR) during summer and winter across two regions in Portugal. Body condition was negatively correlated with temperature, while the relationship between BMR and temperature varied seasonally. In
Marina Sentís   +7 more
wiley   +1 more source

The Conventional and Breakthrough Tool for the Study of L-Glutamate Transporters

open access: yesMembranes
In our recent report, we clarified the direct interaction between the excitatory amino acid transporter (EAAT) 1/2 and polyunsaturated fatty acids (PUFAs) by applying electrophysiological and molecular biological techniques to Xenopus oocytes.
Kanako Takahashi, Kaoru Sato
doaj   +1 more source

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