Results 101 to 110 of about 92,735 (222)
BINge: Multispecies Ortholog Clustering for Differential Gene Expression Analyses
Molecular Ecology Resources, Volume 26, Issue 4, May 2026.ABSTRACT Differential gene expression (DGE) analysis enables researchers to investigate the link between gene expression and the phenotypic responses observed in organisms across time, experimental, or field conditions. Accurate quantification of gene expression is essential when performing DGE experiments, with a range of methods having been developed
Zachary Stewart +3 more
wiley +1 more source
STAT Signaling and Its Anti‐Apoptotic Effects in Dehydrated Xenopus laevis
Biology of the Cell, Volume 118, Issue 5, May 2026.Dehydrated Xenopus laevis showed increased STAT3 and downstream anti‐apoptotic protein activation in the liver, whereas skeletal muscle saw increased STAT5 and downstream anti‐apoptotic protein activation, and decreased STAT1 activation. Collectively, these adaptations lead to decreased apoptosis, likely serving to protect against aestivation‐induced ...
Yulia Biggar +3 more
wiley +1 more source
Control Strategies in Guanine Biocrystallization
Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.Biological guanine crystals produce spectacular photonic phenomena in animals and hold great promise as new, sustainable optical materials. We review how organisms precisely control the structure, morphologies, and resulting optical properties of these crystals using a set of ingenious ‘design’ strategies, including control of pH, template‐directed ...
Shashanka S. Indri +2 more
wiley +2 more sources
Opening closed inward rectifier potassium channel doors
British Journal of Pharmacology, Volume 183, Issue 10, Page 2197-2218, May 2026.Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger +3 more
wiley +1 more source
European Journal of Neuroscience, Volume 63, Issue 9, May 2026.This work provides a potential new link between the anticonvulsive Topiramate, the deacetylase Sirt‐1 and the cholinergic signalling, suggesting that Topiramate may modulate cholinergic pathways in a Sirt‐1 depended manner. ABSTRACT Although some forms of epilepsy directly result from mutations in nicotinic acetylcholine receptors, none of the ...
Marie‐Luise Kümmel
wiley +1 more source
Histone Density and Dynamics Shape Mitotic Chromatid Architecture in Xenopus Egg Extracts
Genes to Cells, Volume 31, Issue 3, May 2026.Histone chaperones and chromatin remodelers modulate histone density and dynamics. The resulting local chromatin properties are integrated with DNA reconfiguration activities mediated by condensins and topoisomerase IIα to shape the global architecture of mitotic chromosomes.
Keishi Shintomi +3 more
wiley +1 more source
Journal of Anatomy, Volume 248, Issue 5, Page 784-805, May 2026.The expression of various genes involved in synapse development, stability and/or function was studied in developing mechanosensory neuromasts and electrosensory ampullary organs in sterlet sturgeon. Most were shared, including Slc17a8, Slc1a3 and Nrxn3, but Cbln18 was neuromast‐restricted and Tulp1 was ampullary organ‐restricted.
Alexander S. Campbell +6 more
wiley +1 more source
Journal of Computational Chemistry, Volume 47, Issue 11, 30 April 2026.Bulky residues constrict the central pore of WT SoPIP2;1, generating high energy barriers for both O2 and CO2 and preventing gas permeation. ABSTRACT Aquaporins (AQPs) are classical water channels that also conduct small gas molecules such as O2$$ {\mathrm{O}}_2 $$ and CO2$$ {\mathrm{CO}}_2 $$ across the membrane.
Ahmad Raeisi Najafi +5 more
wiley +1 more source
Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade +2 more
wiley +1 more source