Results 141 to 150 of about 167,815 (303)
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Generation and Care of Xenopus laevis and Xenopus tropicalis Embryos.
Marcin Wlizla, Sean McNamara, M. Horb
semanticscholar +1 more source
Effect of intercalating agents on RNA polymerase I promoter selection in Xenopus laevis.
Steven C. Pruitt, R H Reeder
openalex +2 more sources
Integrin and ligand-independent PDGFr signaling synergistically contribute to directional migration of Xenopus mesendoderm [PDF]
Crystal Richardson +3 more
openalex +1 more source
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Epitranscriptomics as a Candidate Universal Modulator of Dormancy Transitions
Dormancy is presented as a conserved, reversible survival program in which epitranscriptomic RNA modifications are proposed to provide a rapid, energy‐efficient layer that establishes, maintains, and terminates the state by modulating mRNA stability, translation, and localization.
Ehsan Pashay Ahi
wiley +1 more source
Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes
Y. Sasai +5 more
semanticscholar +1 more source
Effects of Ginsenosides on Vanilloid Receptor (VR1) Channels Expressed in Xenopus Oocytes
Se-Yeon Jung +9 more
openalex +1 more source
ABSTRACT Background Chronic pain, which is often unrelated to ongoing injury, is poorly understood and difficult to treat. Genetic studies have identified voltage‐gated sodium (Nav) channels, particularly gain‐of‐function mutations such as L858F and R1150W in human NaV1.7, as involved in the development of chronic pain. Methods A chronic pain model was
Serena Mares Malta +7 more
wiley +1 more source

