Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal+7 more
wiley +1 more source
Association of TCTP with Centrosome and Microtubules
Translationally Controlled Tumour Protein (TCTP) associates with microtubules (MT), however, the details of this association are unknown. Here we analyze the relationship of TCTP with MTs and centrosomes in Xenopus laevis and mammalian cells using ...
Mariusz K. Jaglarz+7 more
doaj +1 more source
Summary DEADSouth mRNA is a component of germ plasm in Xenopus laevis and encodes a DDX25 DEAD-box RNA helicase. To determine the intracellular localization of DEADSouth protein, we injected mRNA encoding DEADSouth tagged with mCherry fluorescent protein
Takeshi Yamaguchi+3 more
doaj +1 more source
The glial Na+ pump regulates [K+]o during neuronal activity, and the neuronal version restores [K+]o to baseline. Spreading depression‐related rise of K+ does not cause SD propagation via suppression of Na+/K+‐ATPase or glutamate transport. ABSTRACT Neuronal activity in the central nervous system is associated with a [K+]o transient that is swiftly ...
Brian Skriver Nielsen+6 more
wiley +1 more source
Evaluation of the genotoxic and teratogenic potential of a municipal sludge and sludge-amended soil using the amphibian Xenopus laevis and the tobacco: Nicotiana tabacum L. var. xanthi Dulieu [PDF]
The toxic, genotoxic and teratogenicpotential of amunicipal sewage sludge was assessed using the micronucleus assay on the larvae of the amphibianXenopuslaevis and with the tobacco somatic mutation test using the yellow–green xanthiDulieu mutant a1+/a1 ...
Chenon, Pascale+4 more
core +2 more sources
Unequal contribution of native South African phylogeographic lineages to the invasion of the African clawed frog, Xenopus laevis, in Europe [PDF]
Due to both deliberate and accidental introductions, invasive African Clawed Frog (Xenopus laevis) populations have become established worldwide. In this study, we investigate the geographic origins of invasive X.
Charlotte De Busschere+6 more
doaj +2 more sources
Mitochondrial tRNAGlu 14687A>G May Be A Novel Mutation for Type 2 Diabetes Mellitus
We identified a novel mitochondrial tRNAGlu 14687A>G mutation in a Han Chinese pedigree with diabetes; the m.14687A>G mutation occurred at a conserved nucleotide of tRNAGlu, which was important for tRNA structure and function. Using a cybrid cell model, we found that mutant cells exhibited much more severe mitochondrial dysfunctions than control cells,
Xiaojuan Rao+3 more
wiley +1 more source
A comparative analysis of transcription factor expression during metazoan embryonic development [PDF]
During embryonic development, a complex organism is formed from a single starting cell. These processes of growth and differentiation are driven by large transcriptional changes, which are following the expression and activity of transcription factors (TFs).
arxiv +1 more source
A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis
Summary: DNA replication in the embryo of Xenopus laevis changes dramatically at the mid-blastula transition (MBT), with Y RNA-independent random initiation switching to Y RNA-dependent initiation at specific origins.
Christo P. Christov+6 more
doaj
Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy+7 more
wiley +1 more source