Results 111 to 120 of about 157,699 (364)

Using the Xenopus Developmental Eye Regrowth Stystem to Distinguish the Role of Developmental Versus Regenerative Mechanisms [PDF]

open access: yes, 2019
A longstanding challenge in regeneration biology is to understand the role of developmental mechanisms in restoring lost or damaged tissues and organs.
Guerin, Dylan J.   +2 more
core   +1 more source

The Many Faces of Xenopus: Xenopus laevis as a Model System to Study Wolf–Hirschhorn Syndrome

open access: yesFrontiers in Physiology, 2019
Wolf–Hirschhorn syndrome (WHS) is a rare developmental disorder characterized by intellectual disability and various physical malformations including craniofacial, skeletal, and cardiac defects.
Micaela Lasser   +4 more
doaj   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

The epithelium of the dorsal marginal zone of Xenopus has organizer properties [PDF]

open access: yes, 1992
We have investigated the properties of the epithelial layer of the dorsal marginal zone (DMZ) of the Xenopus laevis early gastrula and found that it has inductive properties similar to those of the entire Spemann organizer.
Keller, Ray, Shih, John
core  

Random Networks of Spiking Neurons: Instability in the Xenopus tadpole moto-neural pattern [PDF]

open access: yes, 2000
A large network of integrate-and-fire neurons is studied analytically when the synaptic weights are independently randomly distributed according to a Gaussian distribution with arbitrary mean and variance. The relevant order parameters are identified, and it is shown that such network is statistically equivalent to an ensemble of independent integrate ...
arxiv   +1 more source

Xenopus laevis as a Model Organism for the Study of Spinal Cord Formation, Development, Function and Regeneration

open access: yesFrontiers in Neural Circuits, 2017
The spinal cord is the first central nervous system structure to develop during vertebrate embryogenesis, underscoring its importance to the organism. Because of its early formation, accessibility to the developing spinal cord in amniotes is challenging,
Laura N. Borodinsky
doaj   +1 more source

Obtaining Xenopus laevis Embryos

open access: yesCold Spring Harbor Protocols, 2020
The embryos of the African clawed frog, Xenopus laevis, are a powerful substrate for the study of complex fundamental biological and disease mechanisms in neurobiology, physiology, molecular biology, cell biology, and developmental biology. A simple and straightforward technique for generating a large number of developmentally synchronized embryos is ...
Marko E. Horb   +3 more
openaire   +4 more sources

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra   +3 more
wiley   +1 more source

Mitotic spindle scaling during Xenopus development by kif2a and importin α. [PDF]

open access: yes, 2012
Early development of many animals is characterized by rapid cleavages that dramatically decrease cell size, but how the mitotic spindle adapts to changing cell dimensions is not understood.
HEALD, Rebecca, Wilbur, Jeremy
core   +2 more sources

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