Results 51 to 60 of about 9,272 (178)

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Molecular insights into electroreceptor ribbon synapses from differential gene expression in sturgeon lateral line organs

Journal of Anatomy, EarlyView.
The expression of various genes involved in synapse development, stability and/or function was studied in developing mechanosensory neuromasts and electrosensory ampullary organs in sterlet sturgeon. Most were shared, including Slc17a8, Slc1a3 and Nrxn3, but Cbln18 was neuromast‐restricted and Tulp1 was ampullary organ‐restricted.
Alexander S. Campbell, Martin Minařík, David Buckley, Tanmay Anand, David Gela, Martin Pšenička, Clare V. H. Baker   +6 more
wiley   +1 more source

Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephaly

Genome Medicine, 2021
Background Coat protein complex 1 (COPI) is integral in the sorting and retrograde trafficking of proteins and lipids from the Golgi apparatus to the endoplasmic reticulum (ER).
William L. Macken, Annie Godwin, Gabrielle Wheway, Karen Stals, Liliya Nazlamova, Sian Ellard, Ahmed Alfares, Taghrid Aloraini, Lamia AlSubaie, Majid Alfadhel, Sulaiman Alajaji, Htoo A. Wai, Jay Self, Andrew G. L. Douglas, Alexander P. Kao, Matthew Guille, Diana Baralle   +16 more
doaj   +1 more source

Pinopsin Regulates Melatonin Production and Daily Locomotor Activity: Functional Insights From Gene‐Edited Xenopus Tadpoles

Journal of Pineal Research, Volume 78, Issue 2, March 2026.
ABSTRACT Circadian rhythm alignment depends on environmental light detection via opsins. Pinopsin, originally identified in the pineal organ of birds and later in amphibian pineal complex and eyes, may play a role in this process, though its function has not been genetically tested.
Neda Heshami, Ricardo D. Romero, Flavio S. J. de Souza, Gabriel E. Bertolesi, Sarah McFarlane   +4 more
wiley   +1 more source

Is adult cardiac regeneration absent in Xenopus laevis yet present in Xenopus tropicalis?

Cell & Bioscience, 2018
We recently used an endoscopy-based resection method to explore the consequences of cardiac injury in adult Xenopus laevis, obtaining the result that the adult Xenopus heart is unable to regenerate.
Lindsey Marshall, Fabrice Girardot, Barbara A. Demeneix, Laurent Coen   +3 more
doaj   +1 more source

QuickProt: A Fast and Accurate Homology‐Based Protein Annotation Tool for Non‐Model Organisms to Advance Comparative Genomics

Molecular Ecology Resources, Volume 26, Issue 2, February 2026.
ABSTRACT The rapid growth of genome sequencing has outpaced the development of efficient annotation tools, especially for species lacking transcriptome data. To address this challenge, we present QuickProt, a fast, accurate and user‐friendly homology‐based protein annotation tool.
Guisen Chen, Hehe Du, Zhenjie Cao, Ying Wu, Chen Zhang, Yongcan Zhou, Jingqun Ao, Yun Sun, Zihao Yuan   +8 more
wiley   +1 more source

The behaviour–performance continuum: how does individual variation in locomotor abilities relate to behaviour?

Biological Reviews, Volume 101, Issue 1, Page 486-518, February 2026.
ABSTRACT A series of terminological, technical, conceptual, and statistical challenges present themselves when trying to study correlations between measures of performance abilities (what an animal can do) and behavioural traits (what an animal chooses to do).
Vincent Careau, Paul Agnani, Nicolas Bonin, Theodore Garland Jr   +3 more
wiley   +1 more source

Metabolomic approach for identifying and visualizing molecular tissue markers in tadpoles of Xenopus tropicalis by mass spectrometry imaging

Biology Open, 2016
In developmental and cell biology it is crucial to evaluate the dynamic profiles of metabolites. An emerging frog model system using Xenopus tropicalis, whose genome sequence and inbred strains are available, is now ready for metabolomics investigation ...
Naoko Goto-Inoue, Akihiko Kashiwagi, Keiko Kashiwagi, Tsukasa Mori   +3 more
doaj   +1 more source

Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. [PDF]

PLoS ONE, 2013
How cells integrate multiple patterning signals to achieve early endoderm regionalization remains largely unknown. Between gastrulation and neurulation, retinoic acid (RA) signaling is required, while Wnt/β-catenin signaling has to be repressed for the ...
Tiejun Zhang, Xiaogang Guo, Yonglong Chen   +2 more
doaj   +1 more source

Expression of Xenopus tropicalis HNF6/Onecut-1

The International Journal of Developmental Biology, 2009
Onecut genes belong to a family of transcription factors that are known to be important in embryonic development. In the present study, we analyzed the pattern of expression of Onecut-1/HNF6 in Xenopus tropicalis using RT-PCR and whole mount in situ hybridization.
Kim E, Haworth, Branko, Latinkic
openaire   +3 more sources