Results 71 to 80 of about 29,864 (273)
The Ethics of Xenotransplantation [PDF]
Journal of Applied Philosophy, 2000 Xenotransplantation--moving organs or cells from one species to another--is currently being actively researched as a possible contribution to the problem of a global shortage of human organs for transplants. Should xenotransplantation be encouraged, permitted, frowned upon or forbidden?
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BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
Generation of RAG2 Knockout Immune-Deficient Miniature Pigs
AnimalsRecombination-activating genes (RAGs) play a crucial role in the V(D)J recombination process and the development of immune cells. The development of the immune system and its mechanisms in pigs exhibit greater similarity to those of humans compared to ...
Jing Wang +8 more
doaj +1 more source
Evaluation of canine teeth crown reduction technique in macaques
Laboratory Animal Research, 2020 Background The reduction of canine teeth in adult males in whom permanent canine teeth eruption occurs should be considered due to the safety of humans or other monkeys.
Su-Mi Kim, Jong-Min Kim
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The 2021 IXA Keith Reemtsma Lecture: Moving xenotransplantation to the clinic
Xenotransplantation, 2021 Keith Reemtsma was a pioneer in xenotransplantation, the Honorary Founding President of the International Xenotransplantation Association (in 1998), and a wonderful personality. It is a privilege to be invited to give this lecture in his memory.
D. Cooper
semanticscholar +1 more source
Immunobiology of xenotransplantation [PDF]
Transplant International, 2000 The transplantation of organs between disparate species is hindered by severe immune responses of the recipient against the graft. These immune responses gives rise to hyperacute and acute vascular rejection and to cellular rejection. Research during the past decade has shed light on the elements of the immune system responsible for the rejection of ...
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Macrophages in xenotransplantation [PDF]
Korean Journal of Transplantation, 2019 Xenotransplantation refers to organ transplantation across species. Immune rejection of xenografts is stronger and faster than that of allografts because of significant molecular differences between species. Recent studies have revealed the involvement of macrophages in xenograft and allograft rejections.
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Molecular Tweezers for Biomimetic Recognition of Carbohydrates
ChemBioChem, EarlyView.Molecular tweezers have emerged as effective binders for biomolecules such as lipids, nucleic acids, and proteins, eliciting biological activities. Tweezer molecules, which exploit an open and adaptive binding cavity, can target relatively large guests, such as oligosaccharides and glycans, and often provide some advantages over corresponding ...
Francesco Milanesi +3 more
wiley +1 more source
Cell Transplantation, 2013 A positive effect on the future development of cells, which have been cooled to low suprazero temperatures and then thawed, has been observed before and is not new.
Vladimir Isachenko +3 more
doaj +1 more source
Xenotransplantation, 2020 Many genetically multi‐modified donor lines for xenotransplantation have a background of domestic pigs with rapid body and organ growth. The intrinsic growth potential of porcine xeno‐organs may impair their long‐term function after orthotopic ...
Arne Hinrichs +18 more
semanticscholar +1 more source