Results 121 to 130 of about 35,510 (301)
BRIGHT is a newly developed live‐cell imaging system that integrates cascade amplification with background denoising through the bivalent binding capability and antigen‐dependent stability of a bivalent fluorescent nanobody targeting ALFA peptides.
Lei Feng +9 more
wiley +1 more source
Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation [PDF]
Naive human embryonic stem cells (hESCs) can be derived from primed hESCs or directly from blastocysts, but their X chromosome state has remained unresolved.
Bonora, Giancarlo +10 more
core +1 more source
Supplementary Table 1 from The Histone Deacetylase Inhibitor Abexinostat Induces Cancer Stem Cells Differentiation in Breast Cancer with Low <i>Xist</i> Expression [PDF]
Marion A. Salvador +13 more
openalex +1 more source
Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression. [PDF]
Long non-coding RNA Xist plays a crucial role in establishing and maintaining X-chromosome inactivation (XCI) which is a paradigm of long non-coding RNA-mediated gene regulation.
Minghui Yue +5 more
doaj +1 more source
Artificial intelligence for risk assessment and outcome prediction in malignant haematology
Machine learning models allow for dynamic and scalable risk stratification and outcome prediction. Different modalities of data such as electronic health records, patient genetics or laboratory results can be used as input. ML models autonomously select features weighing their prognostic value. Methods of model explainability in feature selection allow
Jan‐Niklas Eckardt +3 more
wiley +1 more source
Sex in Immune Cells and Parasitic Diseases — A Complex Relationship
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker +2 more
wiley +1 more source
GIVE: portable genome browsers for personal websites. [PDF]
Growing popularity and diversity of genomic data demand portable and versatile genome browsers. Here, we present an open source programming library called GIVE that facilitates the creation of personalized genome browsers without requiring a system ...
Alvin Zheng +31 more
core +2 more sources
Sex Differences in Asthma Pathogenesis
ABSTRACT There is a sex difference in asthma prevalence and asthma‐related morbidity that changes from childhood into different reproductive stages of life. The impact of sex hormone signaling on asthma pathogenesis has been partially elucidated using large cohort human studies, human cells, and animal models. Androgens decreased airway inflammation by
Kaitlin E. McKernan +2 more
wiley +1 more source
Background Long noncoding RNAs (lncRNAs) have been reported to be associated with dermis process during burn wound healing. This study aimed to investigate the role of lncRNA X-inactive specific transcript (XIST) in human skin fibroblasts (HSF) and ...
Wei Cao, Youping Feng
doaj +1 more source
Cosmological parameter constraints for Horndeski scalar-tensor gravity [PDF]
We present new cosmological parameter constraints for general Horndeski scalar-tensor theories, using CMB, redshift space distortion, matter power spectrum and BAO measurements from the Planck, SDSS/BOSS and 6dF surveys.
Nicola, Andrina, Noller, Johannes
core +2 more sources

