Results 101 to 110 of about 16,717 (221)

Molecular and genomic advances in breast cancer: A comprehensive review of predictive and therapeutic innovations

Precision Medical Sciences, Volume 15, Issue 3, Page 164-175, September 2026.
Breast cancer subtypes, estrogen receptor‐positive (ER+), HER2‐enriched, and TNBC, are defined by genomic and epigenetic signatures. Multi‐omics profiling, immunotherapy, liquid biopsy, and AI‐driven radiogenomics enable precision medicine. Tools like Oncotype DX and PAM50 support personalized care.
Samina Malik, Arif Malik, Shahzad Ahmad, Hassan Mohsin, Shazia Iqbal   +4 more
wiley   +1 more source

Identification of regulatory elements flanking human XIST reveals species differences [PDF]

, 2010
Background: The transcriptional silencing of one X chromosome in eutherians requires transcription of the long non-coding RNA gene, XIST.
Carolyn J Brown, Samuel C Chang, Chang, Samuel C., Brown, Carolyn Janet   +3 more
core   +1 more source

LncRNA XIST promotes extracellular matrix synthesis, proliferation and migration by targeting miR-29b-3p/COL1A1 in human skin fibroblasts after thermal injury

Biological Research, 2019
Background Long noncoding RNAs (lncRNAs) have been reported to be associated with dermis process during burn wound healing. This study aimed to investigate the role of lncRNA X-inactive specific transcript (XIST) in human skin fibroblasts (HSF) and ...
Wei Cao, Youping Feng
doaj   +1 more source

Repurposing Agricultural Budgets With Multiple Objectives and Fiscal Constraints: A Multicriteria Decision‐Making Policy Tool Applied to Sub‐Saharan African Countries

Journal of Agricultural Economics, Volume 77, Issue 3, Page 910-927, September 2026.
ABSTRACT Repurposing agricultural public resources toward higher‐return incentives and investments can help transform agri‐food systems. This is important for low‐income countries, especially in sub‐Saharan Africa, where limited budgets restrict options for boosting agricultural spending.
Marco V. Sánchez, Martín Cicowiez, Lucia Battaglia, Valentina Pernechele   +3 more
wiley   +1 more source

Defining the sequence requirements for Xist function in X inactivation [PDF]

, 2022
Mammalian genomes encode thousands of long non-coding (lnc) RNAs, many with important functions including the regulation of gene expression, yet, how lncRNAs function remains largely unexplored.
Chau, Anthony Chun-Yu
core  

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, Volume 81, Issue 9, Page 3039-3070, September 2026.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter, Ian M. Adcock, Cristina Benito‐Villalvilla, Rodolfo Bianchini, Leif Bjermer, Gaetano Caramori, Luigi Cari, Kian Fan Chung, Zuzana Diamant, Ibon Eguiluz‐Gracia, Edward F. Knol, Milos Jesenak, Francesca Levi‐Schaffer, Giuseppe Nocentini, Liam O'Mahony, Oscar Palomares, Frank Redegeld, Milena Sokolowska, Betty Van Esch, Marco Zurlo, Cristiana Stellato   +20 more
wiley   +1 more source

Extensive remodelling of XIST regulatory networks during primate evolution

, 2023
Unravelling how gene regulatory networks are remodelled during evolution is crucial to understand how species adapt to environmental changes. We addressed this question for X-chromosome inactivation, a process essential to female development that is ...
Dong, Michael, Castel, Gaël, Alfeghaly, Charbel, Heard, Edith, Rognard, Cloé, Loda, Agnese, Rougeulle, Claire, Savatier, Pierre, Cazottes, Emmanuel, Aksoy, Irène, Villacorta, Laura, Morey, Céline   +11 more
core   +1 more source

YY1 Tethers Xist RNA to the Inactive X Nucleation Center [PDF]

, 2011
SummaryThe long noncoding Xist RNA inactivates one X chromosome in the female mammal. Current models posit that Xist induces silencing as it spreads along X and recruits Polycomb complexes.
Jeon, Yesu, Lee, Jeannie T., Yesu Jeon, Jeannie T. Lee   +3 more
core   +1 more source

Males with High-XIST display female-like patterns.

, 2019
A) A subset of males have XIST expression equivalent to female expression levels (High-XIST males). B) When compared to Low-XIST males, High-XIST males show significantly stronger relationships between the candidate miRNA and DMX gene.
Wan L. Lam (7255919), Carolyn J. Brown (7255922), Greg L. Stewart (7255916), Adam P. Sage (6427013), Erin A. Marshall (6427025)   +4 more
core   +1 more source

Evolution from XIST-independent to XIST-controlled X-chromosome inactivation : epigenetic modifications in distantly related mammals [PDF]

, 2011
CITATION: Chaumeil, J. et al. 2011. Evolution from XIST-independent to XIST-controlled X-chromosome inactivation : epigenetic modifications in distantly related mammals. PLoS ONE, 6(4): e19040, doi:10.1371/journal.pone.0019040.The original publication is
Jennifer A. Marshall Graves, Marshall Graves Jennifer A., Waters, Paul, Graves, Jennifer A. Marshall, Gilbert, Clement, Robinson Terence J., Chaumeil Julie, Terence J. Robinson, Julie Chaumeil, Clément Gilbert, Paul D Waters, Edda Koina, Jennifer A Marshall Graves, Robinson, Terence, Paul D. Waters, Koina Edda, Marshall Graves, Jennifer, Chaumeil, Julie, Koina, Edda, Gilbert Clément, Robinson, Terence J., Waters Paul D., Terence J Robinson, Marshall Graves, Jennifer A., Waters, Paul D.   +24 more
core   +2 more sources