Results 181 to 190 of about 16,717 (221)
Phase separation paints Xi with Xist
Michaels, Thomas C. T., Wutz, Anton
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Mechanisms at the Intersection of lncRNA and m6A Biology. [PDF]
Gonzalez SJ +3 more
europepmc +1 more source
Sex differences in the pathogenesis of degenerative knee osteoarthritis: a comparative transcriptomics analysis. [PDF]
Ogunsola AS +7 more
europepmc +1 more source
Xist ribonucleoproteins promote female sex-biased autoimmunity
Autoimmune diseases disproportionately affect females more than males. The XX sex chromosome complement is strongly associated with susceptibility to autoimmunity.
Howard Chang, Yanding Zhao
exaly +2 more sources
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A revision of the human XIST gene organization and structural comparison with mouse Xist
Mammalian Genome, 2000The XIST gene plays an essential role in X Chromosome (Chr) inactivation during the early development of female humans. It is believed that the XIST gene, not encoding a protein, functions as an RNA. The XIST cDNA is unusually long, as its full length is reported to be 16.5 kilobase pairs (kb).
Y K, Hong, S D, Ontiveros, W M, Strauss
openaire +2 more sources
2019
Chromosome balance is critical for normal development. When a condition with extra or missing chromosome exists, the effects are damaging if the balance is not somehow restored. A classic example is Down’s syndrome in humans, which is characterized by trisomy 21.
Gartler, Stanley M. +2 more
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Chromosome balance is critical for normal development. When a condition with extra or missing chromosome exists, the effects are damaging if the balance is not somehow restored. A classic example is Down’s syndrome in humans, which is characterized by trisomy 21.
Gartler, Stanley M. +2 more
openaire +2 more sources
2018
Live imaging gives additional layers of information such as physical dynamics of a molecule of your interest. Aptamer-based green fluorescent protein (GFP) labeling is suitable for visualization of RNA molecules. Here we describe a method to visualize Xist RNA using the Bgl aptamer system.
Osamu, Masui +2 more
openaire +2 more sources
Live imaging gives additional layers of information such as physical dynamics of a molecule of your interest. Aptamer-based green fluorescent protein (GFP) labeling is suitable for visualization of RNA molecules. Here we describe a method to visualize Xist RNA using the Bgl aptamer system.
Osamu, Masui +2 more
openaire +2 more sources
The role of Xist in X-inactivation
Current Opinion in Genetics & Development, 1998The past year has seen important progress in our understanding of the role of the X inactive specific transcript gene (Xist) in the initiation and propagation of X-inactivation. A 35 kb Xist transgene had been shown to recapitulate the functions of the X-inactivation centre, progress has been made towards indentifying factors controlling the randomness
openaire +2 more sources
Clinical and Translational Oncology, 2020
Diffuse intrinsic pontine gliomas (DIPGs) are the most fatal primary brainstem tumors in pediatric patients. The identification of new molecular features, mediating their formation and progression, as non-coding RNAs (ncRNAs), would be of great importance for the development of effective treatments.We analyzed the DIPGs transcriptome with the HTA2.0 ...
M. Á. Velázquez-Flores +6 more
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Diffuse intrinsic pontine gliomas (DIPGs) are the most fatal primary brainstem tumors in pediatric patients. The identification of new molecular features, mediating their formation and progression, as non-coding RNAs (ncRNAs), would be of great importance for the development of effective treatments.We analyzed the DIPGs transcriptome with the HTA2.0 ...
M. Á. Velázquez-Flores +6 more
openaire +2 more sources

