Results 121 to 130 of about 7,632 (199)

Crystal structure of the 5′ → 3′ exoribonuclease Xrn1 [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2011
J. H. Chang, L. Tong
openaire   +1 more source

Envolvimento da ribonuclease humana Dis3L1 em processos de controlo de qualidade da expressão génica [PDF]

, 2011
Tese de mestrado. Biologia (Biologia Humana e Ambiente). Universidade de Lisboa, Faculdade de Ciências, 2011A expressão génica nos eucariotas envolve um número de etapas interligadas desde a transcrição do material genético até à tradução em proteína ...
Cruz, David João Clara da, 1986, Dias, Deodália Maria Antunes, 1952-, Loison, Luísa Romão, 1963-   +2 more
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Structural and biochemical characterization of eukaryotic mRNA decapping activators [PDF]

, 2014
In eukaryotes, mRNA turnover starts with the truncation of 3′ poly(A) tail and proceeds with either 3′-to-5′ degradation by the exosome complex or with decapping followed by 5′-to-3′ degradation by Xrn1.
Sharif, Humayun
core  

Engineering of a conditional allele reveals multiple roles of XRN2 in Caenorhabditis elegans development and substrate specificity in microRNA turnover [PDF]

, 2017
Although XRN2 proteins are highly conserved eukaryotic 5′→3′ exonucleases, little is known about their function in animals. Here, we characterize Caenorhabditis elegans XRN2, which we find to be a broadly and constitutively expressed nuclear protein.
Gaidatzis, Dimos, Großhans, Helge, Miki, Takashi S., Rüegger, Stefan, Stadler, Michael B.   +4 more
core  

XRN1 wt Allele [PDF]

, 2020
openaire   +1 more source

A spring-loaded grip-and-pull mechanism for stepwise RNA duplex unwinding by Xrn1. [PDF]

Nucleic Acids Res
Rhee J, Cho H, Hong S, Yoo J, Jin MS, Jin SW, Chang JH, Tong L, Lee G.   +8 more
europepmc   +1 more source

Initial spliceosomal U4/U6 di-snRNA formation occurs in the cytoplasm of Saccharomyces cerevisiae and requires a guard protein mediated quality control. [PDF]

Nucleic Acids Res
Wang X, Guo J, Li J, Krebber H.
europepmc   +1 more source

Yeast elongation factor homolog New1 protects a subset of mRNAs from degradation by no-go decay. [PDF]

Nucleic Acids Res
Müller M, Tittel LS, Petfalski E, Iyer KV, Kraft AA, Pastore S, Butto T, Winz ML.   +7 more
europepmc   +1 more source

A conserved Lsm8-exosome module maintains RNA splicing fidelity to control fungal stress adaptation and virulence. [PDF]

Stress Biol
Ren Y, Cheng H, Han X, Guo M, Xu C, Yan J, Ge Z, Ma Z, Chen Y.   +8 more
europepmc   +1 more source

Reshaping cancer cell plasticity by P-body dynamics and protein translation. [PDF]

Commun Biol
Senatore E, Rinaldi L, Chiuso F, Bianco AG, Feliciello A.   +4 more
europepmc   +1 more source