Results 191 to 200 of about 150,572 (297)

Reinforcing effects of fentanyl/xylazine mixtures in monkeys responding under a food-versus-drug choice procedure. [PDF]

Behav Pharmacol
Maguire DR.
europepmc   +1 more source

Evaluation of sedation for standing clinical procedures in horses using detomidine combined with buprenorphine [PDF]

Alan Taylor, Browning, Carregaro, Carregaro, Clarke, Clarke, Cruz, David Scott, Frances Henson, Hainisch, Johnston, Joubert, Karen Coumbe, Love, Love, Love, Love, Mama, Muir, Nolan, Polly Taylor, Ringer, Ringer, Ringer, Robertson, Roughan, Senior, Taylor, Taylor, Taylor, Taylor, van Dijk   +31 more
core   +1 more source

Multitechnique Approach for Xylazine Detection: Chemical Spot Tests, Immunoassays, and Scanning Electron Microscopy. [PDF]

ACS Omega
Davis K, Lippincott L, Malenius D, Saleem R, Fu S, Majeed S.   +5 more
europepmc   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Profound Effect of Light on Cysts in X-Linked Retinoschisis. [PDF]

Invest Ophthalmol Vis Sci
Hassan S, Stanley ST, Brandauer E, Hsu Y, Rankin TJ, Laird J, Lobeck B, Thompson JM, Bengen MA, Wang K, Drack AV.   +10 more
europepmc   +1 more source

MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation

Allergy, EarlyView.
In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata, Jaclyn W. McAlees, Julie M. Hargis, Archana Shankar, Shouxiong Huang, Senad Divanovic, Ian P. Lewkowich   +6 more
wiley   +1 more source

Real time, on-site drug checking in low-threshold housing communities. [PDF]

Harm Reduct J
Summers C, Silcox J, Zaragoza S, Rapisarda S, Edelmann A, Chatterjee A, Green TC.   +6 more
europepmc   +1 more source

Validation of Aortic Blood Flow Simulations During Extracorporeal Circulation Using Phase Contrast Magnetic Resonance Imaging

Artificial Organs, EarlyView.
This is the first study assessing in vivo blood flow profiles during extracorporeal circulation (ECC) scenarios. Magnetic resonance imaging data served for the calibration of computational fluid dynamics algorithms, enabling accurate replication of the hemodynamic conditions.
Anna Kathrin Assmann, Sinje Reimers, Jonah S. Schrauder, Lei Qu, Xiangge Yin, Amir Moussavi, Artur Lichtenberg, Susann Boretius, Michael Neidlin, Alexander Assmann   +9 more
wiley   +1 more source

Early evidence of the effects of xylazine-adulterated fentanyl in Ohio. [PDF]

Int J Drug Policy
Rosenblum D, Karandinos G, Unick J, Cauchon D, Ciccarone D.   +4 more
europepmc   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source