Results 41 to 50 of about 157,061 (320)

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

open access: yesHepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr   +19 more
wiley   +1 more source

Xylazine Activates Adenosine Monophosphate-Activated Protein Kinase Pathway in the Central Nervous System of Rats. [PDF]

open access: yesPLoS ONE, 2016
Xylazine is a potent analgesic extensively used in veterinary and animal experimentation. Evidence exists that the analgesic effect can be inhibited using adenosine 5'-monophosphate activated protein kinase (AMPK) inhibitors.
Xing-Xing Shi   +7 more
doaj   +1 more source

Physics of brain dynamics: Fokker-Planck analysis reveals changes in EEG delta-theta interactions in anaesthesia [PDF]

open access: yes, 2009
We use drift and diffusion coefficients to reveal interactions between different oscillatory processes underlying a complex signal and apply the method to EEG delta and theta frequencies in the brain.
A Bahraminasab   +12 more
core   +1 more source

THE CLINICAL EVALUATION OF THE EFFECT OF XYLAZINE IN PREGNANT BUFFALOEs AND CATTLE [PDF]

open access: yesBasrah Journal of Veterinary Research, 2007
The object of this study was to investigate the effect of xylazine administration at dose of (0.05 mg/kg BW) intravenously in late pregnancy of buffaloes and cattle.
M. J. Eesa
doaj   +1 more source

Xylazine: A Drug Adulterant of Clinical Concern

open access: yesCurrent Pain and Headache Reports
The opioid epidemic has been responsible for significant morbidity and mortality in the USA and worldwide. As a result, it is essential to recognize the threat these potent drugs can cause when illicitly used. Specifically, introducing fentanyl as a drug
Amber N. Edinoff   +8 more
semanticscholar   +1 more source

Drug Overdose Deaths Involving Xylazine, United States, 2018–2021

open access: yes, 2023
This study presents trends in drug overdose death rates involving xylazine from 2018 through 2021, overall and by sex. Rates of drug overdose deaths involving xylazine are also presented by age group and race and Hispanic origin from 2020 to 2021, and by
M. Spencer   +3 more
semanticscholar   +1 more source

Clinical assessment of epidural analgesia induced by xylazine-lidocaine combination accompanied by xylazine sedation in calves

open access: yesIrish Veterinary Journal, 2005
The aim of the present study was to investigate whether epidural administration of a xylazine-lidocaine combination accompanied by xylazine sedation would provide satisfactory analgesia for some surgical procedures on 10 calves admitted to the ...
Kamiloglu Alkan   +4 more
doaj   +1 more source

Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. [PDF]

open access: yes, 2014
Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4-/- mice fail to form neuromuscular synapses and die at birth.
Burden, Steven J   +2 more
core   +1 more source

Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to opioid antagonism

open access: yesAddiction Neuroscience
Xylazine is in the unregulated drug supply at increasing rates, usually combined with fentanyl, necessitating understanding of its pharmacology. Despite commentary from politicians, and public health officials, it is unknown how xylazine impacts naloxone
Madigan L. Bedard   +12 more
doaj   +1 more source

The effect of vitamin C at varying times on physiological parameters in rabbits after xylazine anaesthesia [PDF]

open access: yesVeterinaria Italiana, 2011
The effects of vitamin C administration at varying time intervals on rectal temperature, respiratory rates, heart rates and sleeping time following xylazine anaesthesia was evaluated in rabbits.
Godwin Onyeamaechi Egwu   +4 more
doaj  

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