Results 271 to 280 of about 283,339 (312)

Statins Inhibit YAP

Science Signaling, 2014
Statins limit breast cancer cell migration by inhibiting the transcriptional coactivator YAP.
openaire   +1 more source

Role of YAP/TAZ in mechanotransduction

Nature, 2011
Cells perceive their microenvironment not only through soluble signals but also through physical and mechanical cues, such as extracellular matrix (ECM) stiffness or confined adhesiveness. By mechanotransduction systems, cells translate these stimuli into biochemical signals controlling multiple aspects of cell behaviour, including growth ...
DUPONT, SIRIO, MORSUT, LEONARDO, ARAGONA, MARIACELESTE, ENZO, ELENA, GIULITTI, STEFANO, CORDENONSI, MICHELANGELO, ZANCONATO, FRANCESCA, Le Digabel J, Forcato M, Bicciato S, ELVASSORE, NICOLA, PICCOLO, STEFANO   +11 more
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Actin on Yap

Science Signaling, 2011
Stress fibers promote nuclear accumulation of Yap, thus promoting proliferation.
openaire   +1 more source

YAP and TAZ Drive Melanoma through Overlapping and YAP Specific Pathways

2020
Melanoma is an aggressive tumor with a high degree of metastasis and limited therapeutic options. Yes Associated Protein 1 (YAP) and Transcriptional coactivator with PDZ-Binding Motif (TAZ) are transcriptional coregulators implicated in driving tumor progression and metastasis in a wide variety of cancers, including melanoma.
openaire   +1 more source

A YAP-derived peptide blocks YAP-TEAD signaling and suppresses cell proliferation

Cellular Signalling
Yes-associated protein (YAP), a pivotal transcriptional co-activator in cell growth regulation, exerts its function through interactions with transcriptional factors like TEAD. Ectopic activation of YAP causes excessive cell proliferation, leading to multiple human diseases, including cancers.
Qiuyun, Yuan, Xiaoqiang, Xia, Yao, Yuan, Qianming, Chen, Xiaodong, Feng   +4 more
openaire   +2 more sources

Yap

2021
openaire   +1 more source

Yapped

Notes and Queries, 1883
openaire   +2 more sources

Control of stem cell renewal and fate by YAP and TAZ

Nature Reviews Molecular Cell Biology, 2023
Jordan Driskill, Duojia Pan
exaly  

Insights into recent findings and clinical application of YAP and TAZ in cancer

Nature Reviews Cancer, 2023
ZHENGMING WU, Kun Liang Guan, J Matthew Franklin   +2 more
exaly  

Yap, n.²

2023
openaire   +1 more source