Results 121 to 130 of about 7,882 (190)

New Insights into the Role of Inflammatory Pathways and Immune Cell Infiltration in Sleep Deprivation-Induced Atrial Fibrillation: An Integrated Bioinformatics and Experimental Study

Journal of Inflammation Research
Junqing Liang,1,2 Baopeng Tang,1,2 Jun Shen,1,2 Manzeremu Rejiepu,1,2 Yankai Guo,1,2 Xiaoyan Wang,1,2 Shijie Shao,1,2 Fei Guo,3 Qin Wang,4 Ling Zhang1 1Xinjiang Key Laboratory of Cardiac Electrophysiology and Cardiac Remodeling, The First Affiliated ...
Liang J, Tang B, Shen J, Rejiepu M, Guo Y, Wang X, Shao S, Guo F, Wang Q, Zhang L   +9 more
doaj  

TAGLN2 induces resistance signature ISGs by activating AKT-YBX1 signal with dual pathways and mediates the IFN-related DNA damage resistance in gastric cancer

Cell Death and Disease
Recently, various cancer types have been identified to express a distinct subset of Interferon-stimulated genes (ISGs) that mediate therapy resistance.
Huiqin Zhuo, Jingjing Hou, Zhijun Hong, Shuqi Yu, Huifang Peng, Lihua Zhang, Wen Xie, Xuehui Hong   +7 more
doaj   +1 more source

Circ-SAR1A Promotes Renal Cell Carcinoma Progression Through miR-382/YBX1 Axis

Cancer Management and Research, 2020
Xiaolei Zhao,* Zhenhua Zhao,* Wenchao Xu, Hui Liu, Junkai Chang, Weibo Xu, Song Li, Songqiang Cao, Junqing Hou Department of Urology, Huaihe Hospital of Henan University, Kaifeng 475000, People’s Republic of China*These authors contributed equally ...
Zhao X, Zhao Z, Xu W, Liu H, Chang J, Xu W, Li S, Cao S, Hou J   +8 more
doaj  

Extracellular RNA in a single droplet of human serum reflects physiologic and disease states. [PDF]

, 2019
Extracellular RNAs (exRNAs) are present in human serum. It remains unclear to what extent these circulating exRNAs may reflect human physiologic and disease states. Here, we developed SILVER-seq (Small Input Liquid Volume Extracellular RNA Sequencing) to
Calandrelli, Riccardo, Chen, Chien-Ju, Chen, Zhen, Chien, Shu, Liu, Yuan, Qi, Zhijie, Su, H Irene, Wu, Qiuyang, Yan, Zhangming, Zheng, Haizi, Zhong, Sheng, Zhou, Zixu   +11 more
core  

YBX1 promotes type H vessel–dependent bone formation in an m5C-dependent manner

JCI Insight
RNA-binding proteins (RBPs) interact with RNA and ubiquitously regulate RNA transcripts during their life cycle, playing a fundamental role in the progression of angiogenesis-related diseases. In the skeletal system, endothelium-dependent angiogenesis is
Yu-Jue Li, Qi Guo, Ming-Sheng Ye, GuangPing Cai, Wen-Feng Xiao, Sheng Deng, Ye Xiao   +6 more
doaj   +1 more source

5-methylcytosine regulated CCNL2 promotes tumorigenesis and cisplatin resistance of ovarian cancer with therapeutic implications

Journal of Ovarian Research
Backgroud Ovarian cancer (OC) is the most lethal gynecological tumor, primarily due to resistance to chemotherapy. Cyclin L2 (CCNL2) is a novel member of the cyclin family and mainly localized in nucleus.
Kai Zhang, Guiyun Cheng, Wenwen Jiang, Beihua Kong, Shu Yao, Xihan Liu   +5 more
doaj   +1 more source

MDM1 overexpression promotes p53 expression and cell apoptosis to enhance therapeutic sensitivity to chemoradiotherapy in patients with colorectal cancer

Cancer Biology & Medicine
Objective: Identifying biomarkers that predict the efficacy and prognosis of chemoradiotherapy is important for individualized clinical treatment. We previously reported that high murine double minute 1 (MDM1) expression in patients with rectal cancer is
Ningxin Ren, Hongxia Chen, Ying Huang, Jing Jin, Shaosen Zhang, Ruoqing Yan, Mengjie Li, Linlin Zheng, Shuangmei Zou, Yexiong Li, Wen Tan, Dongxin Lin   +11 more
doaj   +1 more source

YBX1 inhibits mitochondrial-mediated apoptosis in ischemic heart through the PI3K/AKT signaling pathway

Frigid Zone Medicine
Myocardial infarction (MI) is associated with higher morbidity and mortality in the world, especially in cold weather. YBX1 is an RNA-binding protein that is required for pathological growth of cardiomyocyte by regulating cell growth and protein ...
Bi Fangfang, Cao Miao, Wang Yuquan, Pan Qingming, Jing Zehong, Bing Danyang, Lyu Lifang, Yu Tong, Li Tianyu, Li Xuelian, Liang Haihai, Shan Hongli, Zhou Yuhong   +12 more
doaj   +1 more source

PGC7 regulates maternal mRNA translation via AKT1-YBX1 interactions in mouse oocytes

Cell Communication and Signaling
Timely and accurate translation of maternal mRNA is essential for oocyte maturation and early embryonic development. Previous studies have highlighted the importance of Primordial Germ cell 7 (PGC7) as a maternal factor in maintaining DNA methylation of ...
Yingxiang Liu, Peiwen Feng, Xing Wei, Hongyu Xu, Mengying Yu, Lei Zhang, Weijie Hao, Zekun Guo   +7 more
doaj   +1 more source

CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription

Cell Death & Disease
Abstract Hypertrophic scar (HS) represents the most prevalent form of skin fibrosis, significantly impacting the quality of life. Despite this, the molecular mechanisms driving HS formation remain largely undefined, impeding the development of effective treatments.
Jianzhang Wang, Juan Du, Yajuan Song, Xiaoying Tan, Junzheng Wu, Tong Wang, Yi Shi, Xingbo Xu, Zhou Yu, Baoqiang Song   +9 more
openaire   +4 more sources