Results 261 to 270 of about 356,347 (342)

Solvent‐Rich Pre‐Coagulation Bath for Tunable Liquid‐State Fusion Enables Robust Two‐Step Polymer Embedded Printing

open access: yesAdvanced Science, EarlyView.
Additive manufacturing enables complex structures, but polymer printing often suffers from poor interlayer fusion and defects induced by heat or binders. A two‐step, room‐temperature strategy based on immersion phase separation (IPS‐E3DP) achieves precise liquid‐state fusion with high structural fidelity, enhanced mechanical performance, broad material
Kaidong Song   +11 more
wiley   +1 more source

Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization

open access: yesAdvanced Science, EarlyView.
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay   +3 more
wiley   +1 more source

THE METABOLISM OF YEAST NUCLEIC ACID IN THE RAT

open access: hybrid, 1949
Paul M. Roll   +3 more
openalex   +1 more source

Yeasts and how they came to be. [PDF]

open access: yes, 2019
Calhoun, Sara   +2 more
core   +1 more source

Enhancing the β‐Oxidation‐Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid

open access: yesAdvanced Science, EarlyView.
The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan   +5 more
wiley   +1 more source

Comparison of MALDI-TOF MS instruments and databases for the identification of uncommon yeasts, <i>Aspergillus</i> spp. and rare filamentous fungi. [PDF]

open access: yesJ Clin Microbiol
Dutkiewicz M   +11 more
europepmc   +1 more source

Biomolecular Interaction Prediction: The Era of AI

open access: yesAdvanced Science, EarlyView.
This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley   +1 more source

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