Results 81 to 90 of about 148,524 (302)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Effects of Fermentation on Proximate, Mineral Elements and Total Antioxidant Activity of Cloves-Cinnamon Formulated Cereal Gruels [PDF]

Journal of Food Quality and Hazards Control
Background: Ogi is a popularly consumed fermented cereal in Nigeria. Concerns have arisen regarding the loss of essential nutrients during processing as pomace.
T. Ozabor, M. Makanjuola, M. Jejeniwa, I. Adekomi, G. Oni, O. Oluwajide, J. Olaitan   +6 more
doaj  

Yeasts at Extreme pH Conditions

Some yeast species exhibit remarkable adaptability to extreme pH conditions, thriving in both highly acidic and highly alkaline environments. Acidophilic yeasts are commonly found in ecosystems such as acid mine drainage sites, acidic water environments,
Turchetti, Benedetta, Buzzini, Pietro, Mugnai, Gianmarco, Sannino, Ciro   +3 more
core   +1 more source

Isolamento e caracterização de leveduras para produção de sidra [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Biotecnologia e Biociências, Florianópolis, 2013A maior parte do plantio nacional de maçãs é feita nos estados da região sul ...
Angioletto, Everton
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The CRISPR/Cas9 system as a molecular strategy to decrease urea production in wine yeasts

, 2017
Genome editing throughout the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein (Cas) represents an emerging engineering approach that could be very useful in industrial yeasts.
Gebbia M., Foschino R., Roth F. P., Belotti A., Vigentini I.   +4 more
core   +2 more sources

THE ROLE OF NUCLEOTIDE SUBSTANSES AND NO-SYNTHASE IN THE IMMUNE PROTECTION OF THE ORGANISM

Разработка и регистрация лекарственных средств, 2019
The present article describes the biochemical mechanisms and the possibility of nucleotides and nucleosides substances naturally produced (i.e. Saccharomyces cerevisiae and others) medicine application in field of correction of pathologically altered ...
V. S. Orlova, E. V. Orlova, A. M. Stoinova, Ya. M. Stanishevskiy   +3 more
doaj  

Microvascular damage is associated with carotid wall structural changes in Systemic Sclerosis: a capillaroscopy and ultrasound‐based observational study

Arthritis Care &Research, Accepted Article.
Introduction Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source