Results 61 to 70 of about 23,846 (225)

Expression and Association of the Yersinia pestis Translocon Proteins, YopB and YopD, Are Facilitated by Nanolipoprotein Particles. [PDF]

PLoS ONE, 2016
Yersinia pestis enters host cells and evades host defenses, in part, through interactions between Yersinia pestis proteins and host membranes. One such interaction is through the type III secretion system, which uses a highly conserved and ordered ...
Matthew A Coleman, Jenny A Cappuccio, Craig D Blanchette, Tingjuan Gao, Erin S Arroyo, Angela K Hinz, Feliza A Bourguet, Brent Segelke, Paul D Hoeprich, Thomas Huser, Ted A Laurence, Vladimir L Motin, Brett A Chromy   +12 more
doaj   +1 more source

The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review

Zoonoses and Public Health, Volume 72, Issue 6, Page 485-500, September 2025.
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans , in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs, Bridgette McNamara, Sarah Hayman, Kim Blasdell, Eugene Athan, Daniel P. O'Brien, Michael Muleme   +6 more
wiley   +1 more source

Interaction of an Acinetobacter baumannii’s Membrane Protein with Human Fibronectin to Evade Immune Response

Chemistry – A European Journal, Volume 31, Issue 45, August 13, 2025.
Interaction of a membrane protein of Acinetobacter baumanii with human fibronectin unraveled using µs‐scale molecular dynamic simulations. Abstract Bacterial resistance and nosocomial infections are serious threats compromising public health in numerous countries.
Laurine Vasseur, Florent Barbault, Antonio Monari   +2 more
wiley   +1 more source

Omics strategies for revealing Yersinia pestis virulence

Frontiers in Cellular and Infection Microbiology, 2012
Omics has remarkably changed the way we investigate and understand life. Omics differs from traditional hypothesis-driven research because it is a discovery-driven approach.
Ruifu eYang, Zongmin eDu, Yanping eHan, Lei eZhou, Yajun eSong, Dongsheng eZhou, Yujun eCui   +6 more
doaj   +1 more source

Harnessing the Potential of mRNA Vaccines Against Infectious Diseases

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
RNA vaccines are promising because of their flexible design, strong immunogenicity, safety and rapid development. Recent advances have enabled mRNA vaccines to target various pathogens, including viruses such as influenza and HIV, bacteria such as Mycobacteria and Pseudomonas aeruginosa, and parasites such as those causing malaria.
Nouran Rezk, Siobhán McClean
wiley   +1 more source

Iron availability and oxygen tension regulate the Yersinia Ysc type III secretion system to enable disseminated infection.

PLoS Pathogens, 2019
The enteropathogen Yersinia pseudotuberculosis and the related plague agent Y. pestis require the Ysc type III secretion system (T3SS) to subvert phagocyte defense mechanisms and cause disease.
Diana Hooker-Romero, Erin Mettert, Leah Schwiesow, David Balderas, Pablo A Alvarez, Anadin Kicin, Azuah L Gonzalez, Gregory V Plano, Patricia J Kiley, Victoria Auerbuch   +9 more
doaj   +1 more source

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Advanced Science, Volume 12, Issue 26, July 10, 2025.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan‐Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar‐Haim, Orit Redy‐Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud   +12 more
wiley   +1 more source

A Heavy Issue: Changes in Body Size in London Before, During and After the Black Death

American Journal of Biological Anthropology, Volume 187, Issue 3, July 2025.
ABSTRACT Objectives The higher mortality rate of the Black Death compared to later epidemics has prompted bioarchaeologists to address the health status of past plague victims and whether this may have influenced the selectivity of the disease. A person's phenotype is the result of a complex interaction between genetic and environmental factors; body ...
Jessica Mongillo, Anthea Cerviero, Nicoletta Zedda, Natascia Rinaldo, Barbara Bramanti   +4 more
wiley   +1 more source

Proteomic Investigation of Human Dental Pulp to Identify Individuals Who Are Pregnant

PROTEOMICS – Clinical Applications, Volume 19, Issue 4, July 2025.
ABSTRACT Biomolecules preserved in dental pulp are increasingly being used to identify individuals in the context of forensics and archaeology. Despite the vast amount of research into host and pathogen DNA, the potential use of physiologically informative proteins preserved in dental pulp has rarely been studied.
Takumi Tsutaya, Kana Fujimoto, Yusuke Nakai, Naana Mori, Ran Iguchi, Akinori Moroi, Kunio Yoshizawa, Koichiro Ueki, Yayoi Kimura, Noboru Adachi   +9 more
wiley   +1 more source

High-throughput analysis of Yersinia pseudotuberculosis gene essentiality in optimised in vitro conditions, and implications for the speciation of Yersinia pestis

BMC Microbiology, 2018
Background Yersinia pseudotuberculosis is a zoonotic pathogen, causing mild gastrointestinal infection in humans. From this comparatively benign pathogenic species emerged the highly virulent plague bacillus, Yersinia pestis, which has experienced ...
Samuel J. Willcocks, Richard A. Stabler, Helen S. Atkins, Petra F. Oyston, Brendan W. Wren   +4 more
doaj   +1 more source