Results 131 to 140 of about 2,438 (147)
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Food and Chemical Toxicology, 2015
The aim of the review was to evaluate the opportunities for diagnosing the zearalenone (ZEN) exposure and intoxication of farm animals by analyzing biological specimens for ZEN residue levels. Metabolism is discussed to be important when evaluating species-specific consequences for the overall toxicity of ZEN.
Sven Dänicke, Janine Winkler
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The aim of the review was to evaluate the opportunities for diagnosing the zearalenone (ZEN) exposure and intoxication of farm animals by analyzing biological specimens for ZEN residue levels. Metabolism is discussed to be important when evaluating species-specific consequences for the overall toxicity of ZEN.
Sven Dänicke, Janine Winkler
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Mycotoxin Research, 2017
This study aimed to investigate a potential modulatory effect of E. coli lipopolysaccharide (LPS) on the kinetics of deoxynivalenol (DON) and zearalenone (ZEN) after pre- or post-hepatic LPS administration to unravel the putative role of the liver. Fifteen barrows were fed a diet containing mycotoxin-contaminated maize (4.59 mg DON/kg feed, 0.22 mg ZEN/
Erik, Bannert +9 more
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This study aimed to investigate a potential modulatory effect of E. coli lipopolysaccharide (LPS) on the kinetics of deoxynivalenol (DON) and zearalenone (ZEN) after pre- or post-hepatic LPS administration to unravel the putative role of the liver. Fifteen barrows were fed a diet containing mycotoxin-contaminated maize (4.59 mg DON/kg feed, 0.22 mg ZEN/
Erik, Bannert +9 more
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2016
A new alkaline-based method was developed for extracting zearalenone (ZEN) from feedstuffs. The procedure was shown to increase the extraction efficiency by 7 to 56 %. The addition of β-glucosidase did not increase the analyzed ZEN concentrationssuggesting ZEN-β-glucosides being of minor importance.
Ueberschär, Karl-Heinz +2 more
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A new alkaline-based method was developed for extracting zearalenone (ZEN) from feedstuffs. The procedure was shown to increase the extraction efficiency by 7 to 56 %. The addition of β-glucosidase did not increase the analyzed ZEN concentrationssuggesting ZEN-β-glucosides being of minor importance.
Ueberschär, Karl-Heinz +2 more
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Toxicon, 2018
The aim of this study was to determine whether exposure to low doses of zearalenone (ZEN) induces changes in the serum biochemical profile and body weights (BW). Pre-pubertal gilts (with BW of up to 14.5 kg) were administered ZEN in daily doses of 5 μg/kg BW (group 1, n = 15), 10 μg/kg BW (group 2, n = 15), 15 μg/kg BW (group 3, n = 15) or placebo ...
Anna, Rykaczewska +6 more
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The aim of this study was to determine whether exposure to low doses of zearalenone (ZEN) induces changes in the serum biochemical profile and body weights (BW). Pre-pubertal gilts (with BW of up to 14.5 kg) were administered ZEN in daily doses of 5 μg/kg BW (group 1, n = 15), 10 μg/kg BW (group 2, n = 15), 15 μg/kg BW (group 3, n = 15) or placebo ...
Anna, Rykaczewska +6 more
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Polish Journal of Veterinary Sciences, 2012
Abstract The objective of this study was to determine the effect of 42-day ZEN intoxication on the presence of Ca2+ in selected ovarian cells from beagle bitches, using the potassium pyroantimonate (PPA) method. Samples were collected from 30 clinically healthy, pre-pubertal, genetically homogeneous animals.
M, Gajecka, B, Przybylska-Gornowicz
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Abstract The objective of this study was to determine the effect of 42-day ZEN intoxication on the presence of Ca2+ in selected ovarian cells from beagle bitches, using the potassium pyroantimonate (PPA) method. Samples were collected from 30 clinically healthy, pre-pubertal, genetically homogeneous animals.
M, Gajecka, B, Przybylska-Gornowicz
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Food and Chemical Toxicology, 2014
A feeding trial with dairy cows fed graded proportions of a Fusarium toxin contaminated maize containing mainly deoxynivalenol (DON) was carried out to relate the plasma levels of DON, zearalenone (ZEN) and their metabolites to the performance. German Holstein cows (n=30) were divided into three groups (n=10 in each): CON (0.02mgZEN and 0.07mgDON, per ...
Janine Winkler +4 more
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A feeding trial with dairy cows fed graded proportions of a Fusarium toxin contaminated maize containing mainly deoxynivalenol (DON) was carried out to relate the plasma levels of DON, zearalenone (ZEN) and their metabolites to the performance. German Holstein cows (n=30) were divided into three groups (n=10 in each): CON (0.02mgZEN and 0.07mgDON, per ...
Janine Winkler +4 more
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Research in Veterinary Science, 2016
The aim of the study was to examine whether the process of exposure to low doses of ZEN generates changes in the hematological and biochemical image of blood serum. During the experiment, pre-pubertal gilts (up to 25kg) were administered per os ZEN at a dose of 40μg/kg BW (Group E, n=18) or placebo (Group C, n=21) on a daily basis for 42days.
Magdalena, Gajęcka +4 more
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The aim of the study was to examine whether the process of exposure to low doses of ZEN generates changes in the hematological and biochemical image of blood serum. During the experiment, pre-pubertal gilts (up to 25kg) were administered per os ZEN at a dose of 40μg/kg BW (Group E, n=18) or placebo (Group C, n=21) on a daily basis for 42days.
Magdalena, Gajęcka +4 more
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Mycotoxin Research, 2016
Both deoxynivalenol (DON), zearalenone (ZEN), and their metabolites are known to modulate immune cells in various species whereby viability and proliferation are influenced. Such effects were rarely examined in horses. Therefore, one aim of the present study was to titrate the inhibitory concentrations of DON, 3-acetyl-DON (3AcDON), de-epoxy-DON (DOM-1)
Barbara, Schumann +4 more
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Both deoxynivalenol (DON), zearalenone (ZEN), and their metabolites are known to modulate immune cells in various species whereby viability and proliferation are influenced. Such effects were rarely examined in horses. Therefore, one aim of the present study was to titrate the inhibitory concentrations of DON, 3-acetyl-DON (3AcDON), de-epoxy-DON (DOM-1)
Barbara, Schumann +4 more
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Journal of Animal Physiology and Animal Nutrition, 2014
SummaryTo investigate the usefulness of follicular fluid (FF) in relation to blood plasma and bile as indicators of exposure of dairy cows to ZEN, DON and their metabolites, a dose–response study was performed with 30 dairy cows. The cows, 10 in each group (named CON; FUS‐50, FUS‐100), received a diet with three different concentrations of Fusarium ...
J, Winkler +8 more
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SummaryTo investigate the usefulness of follicular fluid (FF) in relation to blood plasma and bile as indicators of exposure of dairy cows to ZEN, DON and their metabolites, a dose–response study was performed with 30 dairy cows. The cows, 10 in each group (named CON; FUS‐50, FUS‐100), received a diet with three different concentrations of Fusarium ...
J, Winkler +8 more
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Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
ZEN is a low-molecular-weight food contaminant that is frequently detected in various crops and regions due to its high thermal stability and persistence. It poses a significant threat to the biological nervous system. However, the molecular mechanisms underlying ZEN-induced neurotoxicity remain incompletely understood.
Ting, Xu +7 more
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ZEN is a low-molecular-weight food contaminant that is frequently detected in various crops and regions due to its high thermal stability and persistence. It poses a significant threat to the biological nervous system. However, the molecular mechanisms underlying ZEN-induced neurotoxicity remain incompletely understood.
Ting, Xu +7 more
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