Development of a Reliable UHPLC-MS/MS Method for Simultaneous Determination of Zearalenone and Zearalenone-14-Glucoside in Various Feed Products [PDF]
Frontiers in Chemistry, 2022 A reliable ultra-high-performance liquid chromatography–tandem mass spectrometry method (UHPLC-MS/MS) was developed for the simultaneous determination of two mycotoxins, that is, zearalenone (ZEN) and zearalenone-14-glucoside (ZEN-14G) in formula feed ...
Zhiqi Zhang +2 more
exaly +4 more sources
Zearalenone-14-Glucoside Specifically Promotes Dysplasia of Gut-Associated Lymphoid Tissue: A Natural Product for Constructing Intestinal Nodular Lymphatic Hyperplasia Model [PDF]
Journal of Advanced Research, 2023 Introduction: Zearalenone-14-glucoside (Z14G) is a modified mycotoxin that widely contaminates food across the world. Our preliminary experiment showed that Z14G degrades to zearalenone (ZEN) in the intestine exerting toxicity.
Meihua Yang, Haonan Ruan, Chong-Ming Wu
exaly +4 more sources
Zearalenone-14-Glucoside Is Hydrolyzed to Zearalenone by β-Glucosidase in Extracellular Matrix to Exert Intracellular Toxicity in KGN Cells [PDF]
Toxins, 2022 As one of the most important conjugated mycotoxins, zearalenone-14-glucoside (Z14G) has received widespread attention from researchers. Although the metabolism of Z14G in animals has been extensively studied, the intracellular toxicity and metabolic ...
Meihua Yang, Haonan Ruan, Yong Hou
exaly +4 more sources
Biosynthesis and Characterization of Zearalenone-14-Sulfate, Zearalenone-14-Glucoside and Zearalenone-16-Glucoside Using Common Fungal Strains [PDF]
Toxins, 2018 Zearalenone (ZEN) and its phase II sulfate and glucoside metabolites have been detected in food and feed commodities. After consumption, the conjugates can be hydrolyzed by the human intestinal microbiota leading to liberation of ZEN that implies an ...
Sascha Rohn, Julia Keller, Hans J Kunte
exaly +4 more sources
Cyclodextrins Can Entrap Zearalenone-14-Glucoside: Interaction of the Masked Mycotoxin With Cyclodextrins and Cyclodextrin Bead Polymer [PDF]
Biomolecules, 2019 Zearalenone (ZEN) is a Fusarium-derived xenoestrogenic mycotoxin. In plants, zearalenone-14-O-β-d-glucoside (Z14G) is the major conjugated metabolite of ZEN, and is a masked mycotoxin.
Beáta Lemli +2 more
exaly +4 more sources
Individual and Combined Cytotoxic Effects of Zearalenone and Zearalenone-14-Glucoside in Porcine Intestinal Epithelial Cells [PDF]
Veterinary SciencesZearalenone (ZEN) and its masked form, zearalenone-14-glucoside (Z14G), are common mycotoxins found in feed that can threaten the intestinal health of piglets.
Rui Liu +8 more
doaj +2 more sources
Toxicokinetics, Biotransformation, Excretion, and Tissue Residue of Zearalenone-14-Glucoside in Male Sheep [PDF]
ToxinsZearalenone-14-glucoside (Z14G) is a common modified mycotoxin attracting considerable attention due to its high occurrence in feed and food, and its potential to transform into the parent form zearalenone (ZEN) in vivo.
Jiaxin Qin +9 more
doaj +2 more sources
Applied Sciences (Switzerland), 2023 A reliable high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was established for the simultaneous detection of zearalenone-14-glucoside (ZEN-14G) and its metabolite, zearalenone (ZEN), in the plasma, urine, and various ...
Zhiqi Zhang, Zhizhong Li, Zhiqi Zhang
exaly +3 more sources
Integrated Fermentation, Microbiome and Metabolomic Profiles Reveal Rumen Lipotoxicity Induced by the Masked Mycotoxin Zearalenone-14-Glucoside [PDF]
ToxinsThe ubiquitous presence of modified mycotoxins such as zearalenone-14-glucoside (ZEN-14G) in agricultural resources presents a critical challenge to livestock safety, specifically regarding their capacity to disrupt lipid metabolism and fermentation in ...
Zixin Wang +5 more
doaj +2 more sources
Metabolites, 2023 Mycotoxins are toxic metabolites of molds. Chronic exposure to alternariol, zearalenone, and their metabolites may cause the development of endocrine-disrupting and carcinogenic effects.
Beáta Lemli +2 more
exaly +3 more sources