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Key comparison study—organic solvent calibration solution—gravimetric preparation and value assignment of trans-zearalenone (trans-ZEN) in acetonitrile (ACN)

Metrologia, 2020
The CCQM-K154.a and subsequent CCQM-K154.a.1 comparisons were coordinated by the the Bureau International des Poids et Mesures (BIPM) and the Chinese National Institute of Metrology (NIM) on behalf of the Organic Analysis Working Group (OAWG) of the Comité Consultatif pour la Quantité de Matière (CCQM) for National Measurement Institutes (NMIs) and ...
Josephs, R. D.   +29 more
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Plasma kinetics and matrix residues of deoxynivalenol (DON) and zearalenone (ZEN) are altered in endotoxaemic pigs independent of LPS entry site

Mycotoxin Research, 2017
This study aimed to investigate a potential modulatory effect of E. coli lipopolysaccharide (LPS) on the kinetics of deoxynivalenol (DON) and zearalenone (ZEN) after pre- or post-hepatic LPS administration to unravel the putative role of the liver. Fifteen barrows were fed a diet containing mycotoxin-contaminated maize (4.59 mg DON/kg feed, 0.22 mg ZEN/
Erik, Bannert   +9 more
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Solid Phase Extraction of Zearalenone (ZEN) from Beer Samples Using Natural Zeolite Clinoptilolite and Organo-Zeolites Prior to HPLC Determination

Ekoloji, 2013
Zearalenone (ZEN), is a secondary metabolite with estrogenic properties, is produced by several Fusarium species that colonize cereal grains such as corn, oats, barley, wheat, and grain sorghum in the field and in storage. Because of the toxic effects of ZEN which cause significant human and animal diseases and significant economic losses worldwide ...
Pasınlı, Türker, Henden, Emür
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Residues of zearalenone (ZEN), deoxynivalenol (DON) and their metabolites in plasma of dairy cows fed Fusarium contaminated maize and their relationships to performance parameters

Food and Chemical Toxicology, 2014
A feeding trial with dairy cows fed graded proportions of a Fusarium toxin contaminated maize containing mainly deoxynivalenol (DON) was carried out to relate the plasma levels of DON, zearalenone (ZEN) and their metabolites to the performance. German Holstein cows (n=30) were divided into three groups (n=10 in each): CON (0.02mgZEN and 0.07mgDON, per ...
Janine Winkler   +4 more
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The low doses effect of experimental zearalenone (ZEN) intoxication on the presence of Ca2+ in selected ovarian cells from pre-pubertal bitches

Polish Journal of Veterinary Sciences, 2012
Abstract The objective of this study was to determine the effect of 42-day ZEN intoxication on the presence of Ca2+ in selected ovarian cells from beagle bitches, using the potassium pyroantimonate (PPA) method. Samples were collected from 30 clinically healthy, pre-pubertal, genetically homogeneous animals.
M, Gajecka, B, Przybylska-Gornowicz
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Effects of deoxynivalenol (DON), zearalenone (ZEN), and related metabolites on equine peripheral blood mononuclear cells (PBMC) in vitro and background occurrence of these toxins in horses

Mycotoxin Research, 2016
Both deoxynivalenol (DON), zearalenone (ZEN), and their metabolites are known to modulate immune cells in various species whereby viability and proliferation are influenced. Such effects were rarely examined in horses. Therefore, one aim of the present study was to titrate the inhibitory concentrations of DON, 3-acetyl-DON (3AcDON), de-epoxy-DON (DOM-1)
Barbara, Schumann   +4 more
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Risk assessment for changes in the metabolic profile and body weights of pre-pubertal gilts during long-term monotonic exposure to low doses of zearalenone (ZEN)

Research in Veterinary Science, 2016
The aim of the study was to examine whether the process of exposure to low doses of ZEN generates changes in the hematological and biochemical image of blood serum. During the experiment, pre-pubertal gilts (up to 25kg) were administered per os ZEN at a dose of 40μg/kg BW (Group E, n=18) or placebo (Group C, n=21) on a daily basis for 42days.
Magdalena, Gajęcka   +4 more
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Diagnostic opportunities for evaluation of the exposure of dairy cows to the mycotoxins deoxynivalenol (DON) and zearalenone (ZEN): reliability of blood plasma, bile and follicular fluid as indicators

Journal of Animal Physiology and Animal Nutrition, 2014
SummaryTo investigate the usefulness of follicular fluid (FF) in relation to blood plasma and bile as indicators of exposure of dairy cows to ZEN, DON and their metabolites, a dose–response study was performed with 30 dairy cows. The cows, 10 in each group (named CON; FUS‐50, FUS‐100), received a diet with three different concentrations of Fusarium ...
J, Winkler   +8 more
openaire   +2 more sources

Zearalenone (ZEN) impairs motor function and induces neurotoxicity via inflammatory pathways: Evidence from zebrafish models and molecular docking studies

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
ZEN is a low-molecular-weight food contaminant that is frequently detected in various crops and regions due to its high thermal stability and persistence. It poses a significant threat to the biological nervous system. However, the molecular mechanisms underlying ZEN-induced neurotoxicity remain incompletely understood.
Ting, Xu   +7 more
openaire   +2 more sources

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