Results 11 to 20 of about 20,825 (172)

Zidovudine [PDF]

Infectious Diseases in Obstetrics and Gynecology, 1998
Zidovudine was the first agent approved for treatment of HIV disease, and since its widespread availability in 1987, the pharmacokinetic disposition and clinical effects of ZDV have been extensively evaluated. In addition to its utility as a component of a multidrug combination regimen for the treatment of adult and pediatric HIV-1 infection, it is the
openaire   +3 more sources

Determinants for zidovudine-induced anemia in HIV adult patients: A Thai multicenter study

Archives of Pharmacy Practice, 2014
Objectives: This study was aimed to analyze the prevalence of zidovudine (AZT)-induced anemia, severity and determinants for the anemia in Thai human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients. Materials and Methods: A
Piyawan Kuwalairat, Win Winit-Watjana, Chumphon Community Hospital Antiretroviral Clinic Group   +2 more
doaj   +1 more source

Correlation between plasma glucose and hemoglobin A1c in HIV-infected individuals receiving zidovudine and non-zidovudine containing antiretroviral therapy regimens

HIV Research & Clinical Practice, 2020
Background Hemoglobin A1c (HbA1c) has been used for the diagnosis of diabetes and glycemic monitoring. However, using HbA1c for glycemia estimation has some fallacies in anemic persons.
Thanyalak Saetang, Chutintorn Sriphrapradang, Angsana Phuphuakrat, Somnuek Sungkanuparph   +3 more
doaj   +1 more source

Zidovudine/lamivudine for HIV-1 infection contributes to limb fat loss. [PDF]

PLoS ONE, 2009
Lipoatrophy is known to be associated with stavudine as part of the treatment for HIV infection, but it is less clear if this serious side effect is also related to other nucleoside reverse transcriptase inhibitors like zidovudine.
Marit G A van Vonderen, Michiel A van Agtmael, Elly A M Hassink, Ana Milinkovic, Kees Brinkman, Suzanne E Geerlings, Matti Ristola, Arne van Eeden, Sven A Danner, Peter Reiss, MEDICLAS study group   +10 more
doaj   +1 more source

Combination of Antiretroviral Drugs Zidovudine and Efavirenz Impairs Tumor Growths in a Mouse Model of Cancer

Viruses, 2021
LINE1 retrotransposons, which are thought to be the remnants of ancient integrations of retrovirus-like elements, are aberrantly (re)activated in many cancer cells.
Marcel A. Schneider, Anton A. Buzdin, Achim Weber, Pierre-Alain Clavien, Pieter Borger   +4 more
doaj   +1 more source

ANALYSIS OF MIXED COMBINATIONS OF MEDICINAL PRODUCTS BASED ON ABAKAVIR, LAMIVUDIN, ZIDOVUDIN USING THE METHOD OF MICROCOLONIES LIQUID CHROMATOGRAPHY

Кубанский научный медицинский вестник, 2018
Aim.To develop a technique for the detection and separation of abacavir, lamivudine, zidovudine, both individually and combined with adaptol, azaleptin, analgin, amitriptyline, haloperidol, melipramine, neuleptil, phenobarbital, fluoxetine, and ...
YU. A. GONCHIKOVA, N. V. CHMELEVSKAYA, E. A. ILLARIONOVA   +2 more
doaj   +1 more source

Fluorescence- and TEM-Based Evaluation of Doxorubicin–Zidovudine Combination Therapy in HeLa Cells Using AO/PI Staining [PDF]

EPJ Web of Conferences
Combination chemotherapy is increasingly investigated to improve anticancer efficacy and mitigate resistance associated with single-agent treatments.
Suryan Lakshmi Priya, Karthick V.
doaj   +1 more source

A Comparative Study of the Effect of Different Stabilizers on the Critical Quality Attributes of Self-Assembling Nano Co-Crystals

Pharmaceutics, 2020
Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used orally to manage HIV/AIDS infection. A pseudo one-solvent bottom-up approach was used to develop and produce nano co-crystals of 3TC and AZT. Equimolar amounts of 3TC dissolved in de-ionized
Bwalya A. Witika, Vincent J. Smith, Roderick B. Walker   +2 more
doaj   +1 more source

Antiretroviral prophylaxis to prevent post-natal transmission of HIV through breastfeeding [PDF]

The Pan African Medical Journal, 2008
Although antiretroviral drugs have a crucial role to play in prevention of mother-to-child HIV transmission through breastfeeding, we still have much to learn about how best to use these drugs taking into account the social and biological context of ...
Louise Kuhn
doaj  

Development and validation of a normal-phase HPTLC method for the simultaneous analysis of Lamivudine and Zidovudine in fixed-dose combination tablets

Journal of Pharmaceutical Analysis, 2012
Simultaneous quantification of Lamivudine and Zidovudine in tablets by HPTLC method was developed and validated. The chromatograms were developed using a mobile phase of toluene:ethyl acetate:methanol (4:4:2, v/v/v) on pre-coated plate of silica gel GF ...
Palani Venkatesh, Mahesh Daggumati
doaj   +1 more source