Results 21 to 30 of about 60,681 (284)

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof-of-Concept Study. [PDF]

open access: yesChemMedChem
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Lowe S   +6 more
europepmc   +2 more sources

Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences [PDF]

open access: yes, 2010
Lipoatrophy and metabolic complications of treatment of human immunodeficiency virus (HIV) infection may share common associations with adipose tissue pathology and inflammation.
Hammond, E.L., McKinnon, E., Nolan, D.
core   +2 more sources

Perinatal HIV and Neurodevelopment

open access: yesPediatric Neurology Briefs, 1994
The natural history of HIV disease and neurodevelopmental disorders in 21 perinatally infected children were examined in a collaborative prospective study sponsored by the National Institute of Child Health & Human Development, Rockville, MD.
J Gordon Millichap
doaj   +1 more source

Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial.

open access: yesThe Lancet, 1999
BACKGROUND The AIDS Clinical Trials Group protocol 076 zidovudine prophylaxis regimen for HIV-1-infected pregnant women and their babies has been associated with a significant decrease in vertical HIV-1 transmission in non-breastfeeding women in ...
L. Guay   +18 more
semanticscholar   +1 more source

Nano Co-Crystal Embedded Stimuli-Responsive Hydrogels: A Potential Approach to Treat HIV/AIDS

open access: yesPharmaceutics, 2021
Currently, the human immunodeficiency virus (HIV) that causes acquired immunodeficiency syndrome (AIDS) can only be treated successfully, using combination antiretroviral (ARV) therapy.
Bwalya A. Witika   +3 more
doaj   +1 more source

Comparison of Zidovudine and Tenofovir Based Regimens With Regard to Health-Related Quality of Life and Prevalence of Symptoms in HIV Patients in a Kenyan Referral Hospital

open access: yesFrontiers in Pharmacology, 2018
Aim: Zidovudine and tenofovir form the backbone of antiretroviral therapy in Kenya. However, their side-effects may affect the quality of life (QoL) of patients.
Jilian O. Etenyi   +16 more
doaj   +1 more source

Determinants for zidovudine-induced anemia in HIV adult patients: A Thai multicenter study

open access: yesArchives of Pharmacy Practice, 2014
Objectives: This study was aimed to analyze the prevalence of zidovudine (AZT)-induced anemia, severity and determinants for the anemia in Thai human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients. Materials and Methods: A
Piyawan Kuwalairat   +2 more
doaj   +1 more source

Removal of antiretroviral drugs stavudine and zidovudine in water under UV254 and UV254/H2O2 processes: Quantum yields, kinetics and ecotoxicology assessment.

open access: yesJournal of Hazardous Materials, 2018
The concentration of antiretroviral drugs in wastewater treatment plants (WWTP) effluents and surface waters of many countries has increased significantly due to their widespread use for HIV treatment.
D. Russo   +6 more
semanticscholar   +1 more source

High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia [PDF]

open access: yes, 1998
A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV‐8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV‐8 sVCA
Angeloni, Antonio   +11 more
core   +1 more source

Anemia among HIV Infected Individuals Taking ART with and without Zidovudine at Addis Ababa, Ethiopia

open access: yesEthiopian Journal of Health Sciences, 2018
Background Hematological complications such as Zidovudine(ZDV) associated anemia are among the commonly reported adverse drug reactions of Antiretroviral Therapy(ART).
Zemenu Tamir, Jemal Alemu, A. Tsegaye
semanticscholar   +1 more source

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