Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used orally to manage HIV/AIDS infection. A pseudo one-solvent bottom-up approach was used to develop and produce nano co-crystals of 3TC and AZT. Equimolar amounts of 3TC dissolved in de-ionized
Bwalya A. Witika +2 more
doaj +1 more source
Interventions for neurocognitive dysfunction [PDF]
Purpose of review: To evaluate current barriers to HIV cure strategies and interventions for neurocognitive dysfunction with a particular focus on recent advancements over the last three years. Recent findings: Optimal anti-retroviral therapy (ART) poses
Brew, B, Ellero, J, Lubomski, M
core +2 more sources
Antiretroviral prophylaxis to prevent post-natal transmission of HIV through breastfeeding [PDF]
Although antiretroviral drugs have a crucial role to play in prevention of mother-to-child HIV transmission through breastfeeding, we still have much to learn about how best to use these drugs taking into account the social and biological context of ...
Louise Kuhn
doaj
Immune compromise in HIV-1/HTLV-1 coinfection with paradoxical resolution of CD4 lymphocytosis during antiretroviral therapy: a case report [PDF]
Human immunodeficiency virus type-1 (HIV-1) and human T lymphotropic virus type-1 (HTLV-1) infections have complex effects on adaptive immunity, with specific tropism for, but contrasting effects on, CD4 T lymphocytes: depletion with HIV-1, proliferation
Bangham, C +6 more
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Prevalence of Malaria and Anaemia among HIV Infected Pregnant women Receiving Co-trimoxazole Prophylaxis in Tanzania: A Cross Sectional Study in Kinondoni Municipality. [PDF]
HIV-infected pregnant women are particularly more susceptible to the deleterious effects of malaria infection particularly anaemia. In order to prevent opportunistic infections and malaria, a policy of daily co-trimoxazole prophylaxis without the ...
A Kapito-tembo +34 more
core +1 more source
Increased fetal hemoglobin levels in patients infected with human immunodeficiency virus (HIV1/2)
Fetal hemoglobin was measured in HIV1/2 patients under treatment with combined therapy (zidovudine and a protease inhibitor). A total of 143 patients and 103 normal individuals were investigated by the quantitative method of Betke and the semi ...
A. Poli-Neto +7 more
doaj +1 more source
Inhibition of UGT2B7 Enzyme Activity in Human and Rat Liver Microsomes by Herbal Constituents
The co-use of conventional drug and herbal medicines may lead to herb-drug interaction via modulation of drug-metabolizing enzymes (DMEs) by herbal constituents.
Nurul Huda Abdullah, Sabariah Ismail
doaj +1 more source
Refractory anemia in human immunodeficiency virus: Expect the unexpected
Pure red cell aplasia (PRCA) is an uncommon hematological disorder affecting selectively the erythroid cell lines. PRCA is defined as anemia with normal leukocyte and platelet counts, a corrected reticulocyte count
Sumeet Prakash Mirgh +3 more
doaj +1 more source
A Drug Dosage Table is a Useful Tool to Facilitate Prescriptions of Antiretroviral Drugs for Children in Thailand. [PDF]
Scaling up of antiretroviral treatment (ART) for children in countries like Thailand will require decentralization and management by non-specialist doctors.
Eksaengsri, A +5 more
core +2 more sources
Objective:To compare the preterm delivery rates between pregnant women receiving HAART containing protease inhibitors (HAART-PIs) and zidovudine monotherapy (ZDVm) during pregnancy.Materials and Methods: A retrospective study was ...
Bongkot Chakornbandit +1 more
doaj +1 more source

