Results 51 to 60 of about 20,825 (172)
Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions – A Narrative Review
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background and Aim Human T‐Lymphotropic virus type 1 (HTLV‐1) infection can lead to HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a debilitating chronic neurological disease characterized by progressive lower limb spasticity and autonomic dysfunction.
Meygol Mirzaei Rezaei +11 more
wiley +1 more source
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling is increasingly used to predict infant exposure to medications via breast milk. Existing guidance on reporting of PBPK modeling analyses is unstructured and nonbinding to researchers. We evaluated reporting practices and modeling approaches in published PBPK modeling studies.
Joshua Kiptoo +8 more
wiley +1 more source
Earth and Space Science, Volume 13, Issue 8, August 2026.Abstract Satellite data have been used to estimate the three‐dimensional orientation of features on Mars inferred to be bedding planes to support interpretations of deposit characteristics and depositional environments. Opportunities to ground‐truth these estimates and to understand the geologic information recorded by surfaces measured from orbit are ...
O. A. Kanine +2 more
wiley +1 more source
Incidence and risk factors of anaemia among people on antiretroviral therapy in Harare
Southern African Journal of HIV MedicineBackground: Anaemia is associated with reduced quality of life and increased mortality risk among people living with HIV (PLHIV). Although antiretroviral therapy (ART) reduces the prevalence of anaemia, some patients remain at risk after commencing ART.
Linda A. Mandikiyana Chirimuta +3 more
doaj +1 more source
Química Nova, 2007 An HPLC method was validated to assay lamivudine and zidovudine combined in tablets. The chromatographic separation was carried out using methanol and acetate buffer pH 6.5 (50:50 v/v) and a RP-18 column, as mobile and stationary phase, respectively. The
Ruy Carlos Ruver Beck +5 more
doaj +1 more source
A rare case report of severe aplastic anaemia caused by long-term use of zidovudine
BMC Infectious DiseasesBackground Zidovudine is an antiviral drug used to treat acquired immune deficiency syndrome (AIDS). Anaemia is a common adverse effect of zidovudine that usually occurs in the first 2 to 4 weeks of initial treatment. Here, we describe a patient with HIV
Jing Zhou +6 more
doaj +1 more source
Effects of Chemotherapy on the Elimination of Various Viruses and Viroids from Grapevine
HorticulturaeMaintaining grape cultivation requires the continuous production of healthy propagating material and the control of economically important viruses. For more effective virus eradication, it is beneficial to try chemotherapeutic agents that have not yet ...
Mihaly Turcsan +6 more
doaj +1 more source
“Severe Anemia: A Case Report of an Uncommon Precipitant of Schizophrenia Relapse”
Journal of Blood Medicine, 2023 Krittisak Anuroj, Siwat Chongbanyatcharoen, Romteera Chiencharoenthanakij Department of Psychiatry, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok, ThailandCorrespondence: Krittisak Anuroj, Department of Psychiatry, Faculty of Medicine ...
Anuroj K +2 more
doaj