Results 71 to 80 of about 25,606 (215)

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

Clinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan, Nipun Shrestha, Dhruba Shrestha   +2 more
wiley   +1 more source

Serendipitous Discovery of a Zidovudine Guanidine Complex: A Superior Process for the Production of Zidovudine

, 2016
A superior process for the commercial production of zidovudine (AZT) has been developed. It was discovered that an AZT–guanidine complex formed when a crude zidovudine solution was treated with guanidine.
Bruno K Radatus (2145700)
core   +1 more source

Acceptability of a Dolutegravir Oral Dispersible Film in Term Neonates Born to Mothers Living With HIV

Journal of the International AIDS Society, Volume 29, Issue S1, June 2026.
ABSTRACT Introduction Dolutegravir (DTG) is a key antiretroviral (ARV) drug for children living with HIV, but no specific formulation is available for neonates (<28 days old). One of the DTG formulations evaluated in the PETITE‐DTG trial was a novel 5 mg oral DTG dispersible film (DTG‐Film).
Lario Viljoen, Charlene Purdy, Verah Luke, Samantha du Toit, Marisa Groenewald, Lindee Ganger, Anneke C. Hesseling, Anthony J. Garcia‐Prats, Tim R. Cressey, Adrie Bekker   +9 more
wiley   +1 more source

Int J STD AIDS [PDF]

ObjectiveTo assess trends in hemoglobin recovery among HIV-infected patients initiated on zidovudine-based combined antiretroviral therapy (cART) stratified by baseline hemoglobin level.MethodsHemoglobin data from non-pregnant adult patients initiating ...

core  

Exacerbation of HIV-associated myopathy by zidovudine

, 1991
In the course of a longitudinal study of the neurological complications of HIV infection, we have observed a patient with a strikingly similar presentation whose myopathy preceded zidovudine therapy and worsened during its administration.
Shebert, R, Berger, J, Gregorios, J
core   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, Volume 10, Issue 2, Page 205-241, June 2026.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Zidovudine in Asymptomatic Human Immunodeficiency Virus Infection

, 1990
Zidovudine (AZT) is a potent inhibitor of the replication of the human immunodeficiency virus (HIV), and it has been shown to improve survival in advanced HIV disease.
David K. Booth, Paul A. Volberding, Margaret A. Fischl, Murphy, Robert L, Merigan, Thomas C, Lawrence Corey, Volberding, Paul A, Newton E. Hyslop, Reichman, Richard C, Hardy, W. David, Carla Pettinelli, Richard C. Reichman, Maureen W. Myers, Douglas D. Richman, Stephen W. Lagakos, Balfour, Henry H, Bartlett, John A, Valentine, Fred T, W. David Hardy, Koch, Matthew A, Myers, Maureen W, Fred T. Valentine, Pettinelli, Carla, John G. Bartlett, Hyslop, Newton E, Bartlett, John G, Henry H. Balfour, Fischl, Margaret A, Corey, Lawrence, Booth, David K, Robert L. Murphy, Richman, Douglas D, Hirsch, Martin S, Lagakos, Stephen W, null null, Ruy Soeiro, John A. Bartlett, Thomas C. Merigan, Matthew A. Koch, Martin S. Hirsch, Soeiro, Ruy   +40 more
core   +1 more source

Subgroup Identification via Multiple Change Point Detection: Methods and Applications

WIREs Computational Statistics, Volume 18, Issue 2, June 2026.
Subgroup identification methods facilitate the discovery of clinically meaningful subpopulations with differing disease progression, improving personalized risk assessment and treatment strategies. ABSTRACT Subgroup identification is a significant research area in statistics and machine learning, aiming to partition a heterogeneous population into more
Yaguang Li, Jingli Wang, Da Zhao, Jialiang Li   +3 more
wiley   +1 more source

Sensitivity analysis for generalized estimating equation with non‐ignorable missing data

Scandinavian Journal of Statistics, Volume 53, Issue 2, Page 735-762, June 2026.
Abstract Many incomplete‐data statistical inference procedures are developed under the missing at random (MAR) assumption. However, the MAR assumption has been criticized as being overly strong for real‐data problems, and is unverifiable by using observed data. To handle data that are missing not at random (MNAR), sensitivity analysis has been proposed
Hui Gong, Kin Wai Chan
wiley   +1 more source

Incidence and risk factors of anaemia among people on antiretroviral therapy in Harare

Southern African Journal of HIV Medicine
Background: Anaemia is associated with reduced quality of life and increased mortality risk among people living with HIV (PLHIV). Although antiretroviral therapy (ART) reduces the prevalence of anaemia, some patients remain at risk after commencing ART.
Linda A. Mandikiyana Chirimuta, Tinei Shamu, Cleophas Chimbetete, Chérie Part   +3 more
doaj   +1 more source