Results 71 to 80 of about 27,793 (201)

Zidovudine: a targeted therapy for endemic Burkitt's lymphoma

, 2006
Background: Although cyclophosphamide based regimens can produce remission rates approaching 60 to 80% in endemic Burkitts lymphoma, relapses and refractory disease are fairly common in developing countries, due to advanced stage disease and ...
W Harrington, Harrington, W, Kurokawa, M, Ghosh, S, M Kurokawa, Andela, V, V Andela, Barreto, J Enrique, J Enrique Barreto, S Ghosh   +9 more
core   +1 more source

Haematological safety of perinatal zidovudine in pregnant HIV-1-infected women in Thailand: secondary analysis of a randomized trial [PDF]

, 2007
OBJECTIVES: To respond to the primary safety objective of the Perinatal HIV Prevention Trial 1 (PHPT-1) by studying the evolution of haematological parameters according to zidovudine exposure duration in HIV-1-infected pregnant women. DESIGN: Multicenter,
Lallemant, Marc, Tunthanathip, Preecha, McIntosh, Ken, Techapalokul, Somnuek, Jourdain, Gonzague, Briand, Nelly, Traisathit, Patrinee, Suphanich, Surachet, Chanpoo, Truengta, Le Coeur, Sophie   +9 more
core   +2 more sources

Peptide Thioester and Triazole Derivatives Through On‐Resin Dual‐Modification of Peptide Thiosulfonates

Angewandte Chemie International Edition, Volume 65, Issue 38, 14 September 2026.
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner, Agnes Bergmann, Chenxi Liu, Mira Behnam, Christian Klein, Franziska Thomas   +5 more
wiley   +1 more source

Human immunodeficiency virus treatment-induced adipose tissue pathology and lipoatrophy: Prevalence and metabolic consequences [PDF]

, 2010
Lipoatrophy and metabolic complications of treatment of human immunodeficiency virus (HIV) infection may share common associations with adipose tissue pathology and inflammation.
McKinnon, E., Nolan, D., Hammond, E.L.
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Zidovudine-induced myopathy: A study in Indian patients

, 2010
Context: Literature is replete with studies on zidovudine-induced myopathy after prolonged use (use beyond 270 days on an average). However, all these studies have been done on patients of Caucasian, American and African ethnic origin.
Ashish Bahal, Ambika P Mohanty, Amitabh Sagar   +2 more
core   +1 more source

Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

, 1991
Long-term zidovudine therapy in patients with human immunodeficiency virus (HIV) infection can cause a destructive mitochondrial myopathy with histological features of ragged-red fibres (RRF) and proliferation of abnormal mitochondria.
Moraes, C T, Dalakas, M, Schon, E A, Shanske, S, Arnaudo, E, DiMauro, S   +5 more
core   +1 more source

Survival in 2367 Zidovudine-Treated Patients According to Use of Other Nucleoside Analogue Drugs

, 1998
To evaluate survival according to use of different nucleoside drugs in a routine clinical setting, we studied a large group of zidovudine-treated patients seen in clinics across Europe.
Court Pedersen, Phillips, AN, Christine Katlama, Simon Barton, Pedersen, C, Vella, S, Lundgren, JD, Vella, S., Anders Blaxhult, Blaxhult, A,, Blaxhult, A., Andrew N. Phillips, Stefano Vella, Goebel, FD, Lundgren, J. D., Clotet, B., Barton, S, Pedersen, C., Clotet, B, B. Hirschel, Katlama, C, Phillips, A. N., Hirschel, Bernard, Frank-Detlef Goebel, Barton, S., Goebel, F. D., Hirschel, B, Jens D. Lundgren, Bonaventura Clotet, Katlama, C.   +29 more
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Incidence and risk factors of anaemia among people on antiretroviral therapy in Harare

Southern African Journal of HIV Medicine
Background: Anaemia is associated with reduced quality of life and increased mortality risk among people living with HIV (PLHIV). Although antiretroviral therapy (ART) reduces the prevalence of anaemia, some patients remain at risk after commencing ART.
Linda A. Mandikiyana Chirimuta, Tinei Shamu, Cleophas Chimbetete, Chérie Part   +3 more
doaj   +1 more source

Validação de método por cromatografia líquida de alta eficiência para determinação da lamivudina e zidovudina em comprimidos Validation of a high performace liquid chromatography method for the determina of lamivudine and zidovudine in tablets

Química Nova, 2007
An HPLC method was validated to assay lamivudine and zidovudine combined in tablets. The chromatographic separation was carried out using methanol and acetate buffer pH 6.5 (50:50 v/v) and a RP-18 column, as mobile and stationary phase, respectively. The
Ruy Carlos Ruver Beck, Simone Gonçalves Cardoso, Margareth Linde Athayd, Cristiane Codevilla, Fernanda Kreutz de Oliveira, Sérgio Luiz Dalmora   +5 more
doaj   +1 more source

Effects of zidovudine on auditory functions: enzymology and oxidative stress perspectives

, 2013
The biochemical effects of chronic administration of Zidovudine (commonly used as part of highly active antiretroviral therapy (HAART) for the treatment of Human Immunodeficiency Virus (HIV) type-1) therapy on the intracranial auditory relay centres ...
Adjene, JO, Nwose, Ezekiel, Igbigbi, PS
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