Results 61 to 70 of about 27,793 (201)
Combined Zidovudine and Interferon-α 2a Therapy in Children with Acquired Immune Deficiency Syndrome
, 1992 A study was carried out in five children with acquired immune deficiency syndrome to assess the effect of combined zidovudine/interferon-alpha 2a therapy with that of zidovudine given alone on immunological profiles and plasma zidovudine concentrations ...
M Giovannini +4 more
core +1 more source
Pharmaceutics, 2019 Renal impairment (RI) is a highly prevalent disease which can alter the pharmacokinetics (PK) of xenobiotics, including those that are predominately metabolized.
Kristin E. Follman, Marilyn E. Morris
doaj +1 more source
SPE Polymers, Volume 7, Issue 4, October 2026.Fabrication steps of Alginate, PVA and chitosan hydrogel crosslinked with TEOS for azithromycin drug delivery application. ABSTRACT The main aim of this study was to develop a cost‐effective, pH‐sensitive Alginate (Alg), PVA, and chitosan (Cs) (Alg/PVA/Cs) hydrogel biocompatible polymer for controlled drug release of azithromycin.
Safia Hassan +3 more
wiley +1 more source
Preparation and evaluation of modified release zidovudine tablets [PDF]
, 2011 Zidovudine is a drug used for the treatment of AIDS. The objective of this work was to prepare tablets for modified release of zidovudine. Hydroxypropyl methylcellulose HPMC K100LV and HPMC K4M at 12.50 %, 18.75 % and 25.00 % were used.
Bicheri, María T. L. +3 more
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Role of inosine triphosphate pyrophosphatase gene variant on fever incidence during zidovudine antiretroviral therapy [PDF]
, 2017 Zidovudine, the antiretroviral drug used to treat HIV infection, commonly causes adverse effects, such as systemic fever and gastrointestinal alterations.
Stocco, G +5 more
core +1 more source
THE STUDY OF INFLUENCE OF PREPARATION «COMBIVIR» ON CARBOHYDRATE AND LIPID METABOLISM OF BLOOD SERUM
Современная наука и инновации, 2022 The purpose of this study was to evaluate the effect of the drug «Combivir» on indicators of carbohydrate metabolism and serum lipids in the systemic toxicity study conducted in conditions of chronic experiment.
Elena Olegovna Sergeeva +2 more
doaj
Aging Cell, Volume 25, Issue 10, October 2026.Thymic involution, the age‐related replacement of thymic soft tissue by fat, has been linked to immunosenescence and chronic inflammation. Whether HIV infection affects thymic involution remains unclear. We found that people with HIV on long‐term antiretroviral therapy had more thymic tissue than controls, indicating less thymic involution. More thymic
Manon C. Vanbellinghen +15 more
wiley +1 more source
ObjectiveTo assess trends in hemoglobin recovery among HIV-infected patients initiated on zidovudine-based combined antiretroviral therapy (cART) stratified by baseline hemoglobin level.MethodsHemoglobin data from non-pregnant adult patients initiating ...
core
Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.A series of 18 pyrimidine nucleoside dimers analogues with a short 1,4‐disubstituted 1,2,3‐triazole linkage were synthesized using a click chemistry approach (CuAAC). Analysis of the obtained products was conducted utilizing 1D/2D NMR spectroscopy (1H, 13C, 19F, 15N, and 29Si), mass spectrometry (ESI‐MS), and high‐performance liquid chromatography ...
Dagmara Baraniak +2 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.Es wird eine Strategie zur dualen Modifikation von Peptiden auf der Festphase vorgestellt, die die S‐Alkinylierung von Peptidthiosulfonaten und eine regioselektive, iridiumkatalysierte Azid‐Thioalkin‐Zykloaddition umfasst. Dieses Verfahren ermöglicht zuverlässig den Zugang zu Peptiden mit komplexen, nicht‐kanonischen Modifikationen und ist mit ...
Marius Werner +5 more
wiley +1 more source